Two methods for refining THC distillate, one a Liquid Phase extraction (LPE), the other a Solid Phase extraction (SPE), are presented. The LPE is performed with the distillate suspended in a non polar alkane, then washed with a range of pH balanced saline. This both extracts the water solubles and buffers the solution for proper adsorption during the SPE. The solution is then passed over a chromatography column loaded with MagSil-PR. The alkane is then recovered and the distillate is distilled a second time. The resulting distillate passes PPB residual testing for most common pesticides, specifically Myclobutanil.
We are attempting to follow your remediation of pesticides process and have a few questions. During the purification and buffering with LPE does the order of “washing” matter. You mention 3 separate solutions at varying pH (4, 7, 9) You then stated that your first wash was at a pH of 9. Is it impactful/critical that we start with the pH9 solution? What is the effect of starting with the pH4 solution and then doing pH9 and then pH7(neutral)? Secondly, if your pH4 solution is below 4 is that acceptable (ie.2.4) or impactful?
Terpenes DEFINITELY carry over myclobutanil and several other pesticides, per my experiments utilizing the original form of this tek we developed on crude rather than on distillate. I had to test that side of the equation.