Wakawakalj - Below are some research papers using the SpeedMixer DAC (Dual Asymmetric Centrifuge) for nanoparticles, primarily liposomes. These papers vary in nm range depending on final application from 60nm - 200nm with demonstrated higher encapsulation efficiencies than traditional homogenization methods.
Dual asymmetric centrifugation (DAC)—A new
technique for liposome preparation 2008
Ulrich Massing, Sanja Cicko, Vittorio Ziroli
Matrix liposomes: A solid liposomal formulation
for oral administration 2014
Silvia F. Pantze, Johannes Parmentier, Götz Hofhaus and Gert Fricker
Lecithin-based nanostructured gels for skin
delivery: An update on state of art and
recent applications 2014
Yosra S.R. Elnaggar a,Wessam M. El-Refaie b, Magda A. El-Massik,
Ossama Y. Abdallah
Development and optimization of a new
processing approach for manufacturing
topical liposomes-in-hydrogel drug
formulations by Dual Asymmetric
Sveinung Gaarden Ingebrigtsen, Nataša Škalko-Basnet, Ann
As far as solvent removal goes, that data is all internal at the moment however I am currently working on getting data to publish using Cannabis materials specifically.
Conceptually speaking, during the mix cycle a focal point is created that is a continuous “thin film” exposure allowing for all the solvent to reach the surface and escape. With the low boiling points of butane and propane this is often enough to purge it. To get a cleaner/deeper solvent removal, vacuum can be utilized to drop the temperature even lower and assist in any stubborn gas bubbles. This is all still happening in just a few minutes.