It may be worth trying 1,3-propanediol at a higher concentration by adding it at 2%, 3%, and 4% calculated by weight/weight.
I appreciate the tips there. I will certainly try it more before I write it off. I also have b-cyclodextrin on the way that may have some synergy.
Are you sterile filtering your nanoemulsion?
So I do have sterile filters. I have not filtered it yet. I have not consumed more than 5mL of it but I will certainly filter it before I get heavy metals screening and most certainly for production batches. Any idea if filtering could improve taste? I have noticed a very small amount of foam on the surface of the nano mother liquor (on the order of <1-2mL).
What are the dimensions of your sonotrodeās (aka probeās) horn?
Bit of a personal question donāt you think?? My probe is ~22mm diameter and ~4in long. The horn is ~4.5in. The only issue I am seeing is that the tip of my probe is flared. May prove challenging to schlide a flow cell over and get it to sealā¦
Are you using a jacketed batch reactor vessel now?
I just got my jacketed 1L glass beaker. I was using a waterbath to control the temps before. At first I didnāt think to use the waterbath, and I think I got the solution too hot. Any idea if that could be the source of at least some of the bitterness?
Iām sure this is dabbling into some IP/NDA, but it canāt hurt to askā¦ Is this for cannabinoids in general? Or are we specifically talking about THC? Or are these derivatives of cannabinoids with additional polar side chain groups such as Carmagerol (Polar CBG)?
One of the ingredients is fairly expensive, we have different grades as we do wholesale the delta 8 powder. We have a buick version and our ferrari which is the clear tasteless version.
Sell clear tasteless for 1-1.8 cents per mg for CBD
Cool. From the image it looked it your inlet was the top port. My bad. And thanks for the detailed response.
Depending upon your formulation and nanoemulsion quality, filtering may reduce bitterness. Iām not sure what you mean by ānano mother liquor,ā but a finished nanoemulsion shouldnāt have foam (it should break during processing).
IME high temperature does affect flavor and bitterness, as does long processing time (over-processing). I keep the process liquid at 30-40āC.
I completely agree. @MedicineManHempCo Temperature can definitely impact the formulation, going as far as even disrupting the stability of the particle size if the temperature gets too high. I usually keep my cutoff temperature at 50C before I cease all aspects of the process that generate heat. If you were doing some work with a non-regulated water bath or didnāt keep an eye on the actual temperature there is certainly a chance the temperature could have had a negative impact on the formulation which may or may not mean a change in flavor.
Last night I just tried the n-zorbit maltodextrin from modernist pantry and it worked great, made a stable emulsion with no bitterness and pretty quick onset (within 10-20 minutes.) My concentration was 50mg THC and 100mg CBN in a 4oz syrup.roughly 5% maltodextrin by weight
Not sure if the discussion is still open. But if you are using cyclodextrin, why look to the surfactant? Just the cyclodextrin itself might be able to serve your purpose.
Cyclo dextrin is more of a āstabilizerā for emulsions. The action of encapsulating the active ingredient takes multiple surfactant/emulsifier/biopolymer combinations so even cyclodextrin on its own would macroemulsify at best.
I understand. I was referring to making the standard cyclodextrin-adduct of the cannabinoid concerned, and leaving that in the aqueous solution. That would effectively be a solution, not an emulsion. But yes, you can possibly put only around 20 mg cannabinoid in about 500 mL water. Iāve never gone beyond 10 mg though.
Hey @Ralf your DMās are closed but Iām currently using live resin in my gummies and bitter blockers to mask the flavor. The bitter blocker helps but he issue is that the live resin sticks to my tongue long after the bitter blocker has gone away. Would love to chat with you regarding this if you think you can help.
SoluScience specializes in water soluble ingredients for beverages, however, we do have a team that has created some amazing gummies as well with great taste. I can put you in touch with them if you send me a DM. - Travis
I think there is just a lack of understanding when it comes to food science and flavor modification. I believe thinks that he can mask the bitterness of the terps from the live resin when in reality it is used to help with masking the bitterness of emulsions which for the most part do not include aromatic compounds, just the cannabinoids.
@Littletree you should look into some of the thread of developing an emulsion before trying to figure out your flavor modification.
