for real though I feel like a mental midget around you guys. I am catching up though, i didn’t know shit a month ago
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Acidic conditions will concert your CBD over to some isomer of THC.
The added heat from distilling with the clays in there will make a soup of unknowns.
A good experiment would be to monitor the reaction using HPLC, GCMS, or even TLC to see what is going on.
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I dream of the day when I can afford to do something like that. Right now our lab is limited to spd and vac oven
edit: TLC seems within reach fiscally. Hrm…
Campbell s carts in the making 
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I don’t like the idea of unknowns there is a lot of unknowns when vaping anything already. No making chemical soup for me. Id rather pay someone for chromatography.
edit: apparently Thin Layer Chromatography looks promising as an analytical method for us due to lack of equipment costs in comparison. So, gotta find out what that makes 
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TLC is awesome if there’s only a few compounds in your solution and you have pure samples of each of those compounds. It becomes a little more complex - still possible, but more complex - when you have a lot of compounds and it shows up as a line of marbles.
That’s when you run 2D TLC to see what’s going to degrade and what’s real.
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What do you mean degrade? And what’s the alternative to 2D TLC?
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If it degrades on silica (aka acidic conditions). So this will give a lot of information about what happens when you treat cannabinoids with acid.
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English plz lol
2D TLC?
I swear theres a new term that pops up every day around here
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TLC plates I think is what he’s talking about. I just ordered some reversed-phase plates by Analtech for exactly this.
@anon93688 like this, right? This is CBD / mother liquor samples on silica 60 plates. The spots were colorless until maybe 12 hours passed after drying
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That sounds like a Google nightmare.
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Make sure you search for “TLC Analtech” hahah
(tender lovin’ care)
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Lmao the unsuspecting virgin eyes you just saved
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That one doesn’t look so good.
This TLC is showing different fractions after chromatography. notice how there is a light spot in the first fraction? If I ran 2D TLC on this using a different gradient I could learn a lot of information.
2D TLC is different in that you run the plate a second time with a 90* rotation. This information is useful since it will tell you if what you are making is stable to the stationary phase on the plate.
Edit: had the wrong TLC plate description.
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I know it doesn’t look good
I lost $2 in plates and maybe $0.20 in solvent. Gained a tiny bit of knowledge. Win.
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not trying to put you down. the sample you spotted is overloaded that’s all. you want small spots on the plate so you can see what’s actually going on.
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I did varying dilutions using 1:1 Heptane:ethyl acetate on silica 60 phase plates (not a great choice)
This plate looked the best lmao
Anyone ever used 2D GCMS or LCMS? I remember seeing a vendor demo it when I was at an analytical lab. It impressed me quite a bit
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They have a great sense of humor about the name too. Adventures of Ana L'Tech - a great Chromatographic Comedy.rv - YouTube
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