Hellođ I have a few questions about isomerization. I want to make delta 8 thc from cbd isolate without SPD. I will build my own SPD setup part by part but at the moment it isnât ready.
My plan is:
dissolve cbd isolate in ethanol and put in a BF on a heating mantle with magnetic stirrer.
ad a catalyst and put a reflux condenser on it
heating(150c?) the solution and stir gently
when the isomerization is complete filter the solution through a buchner funnel with filter paper to catch the catalyst.
evaporate the ethanol with a simple vacuum distillation set.
And my questions are:
is it possible to make a delta 8 isomerization without SPD?
wich catalyst can be used for this? (I need a catalyst that is available in Europe)
what is the optimal temperature and time to achieve the best possible result with cbd isolate?
Thereâs plenty of information on the site to answer your question. The search button is the magnifying glass in the upper right hand side of the page.
That said, please donât consume D8 that hasnât been run through SPD. Thereâs a lot of unknown substances in converted in 8 crude that may be potentially unsafe.
Also, the word you are looking for is âcatalystâ, not âisomerâ.
Thanks for the informationsđ
I have used the search function but the amount of informations confused me a bit.
OK, than I have to complete my SPD system first. And sorry for using the wrong wordđ
Isomerization of Cbd issolate I recomend a solvent as carrier of your catalyst and Cbd
Throwing the catalyst directly in the Cbd is not a good idea as off yet
Most isomerizations can be done at temps below 100C
In all my findings the presence of moisture makes D8
And dry conditions make D 9
I wonder if distillation of well preformed isomerizations to D8 is the best cleanup
I find waterwashes with ph swings do more cleaning than distillation does
Not saying that it s not smart to do but
I think that implementing several cleanup steps
Make the cleanest prodduct
That sounds very interesting.
Is ethanol a good carrier for catalysts?
And can you tell me a good catalyst that is available in Europe?
Do you do the water wash instead of the SPD or as extra cleaning before distilling it?
Most isomerizations are done with a acid so water washing is really necessary
Any acid will have a isomerization as result
The art is to find those that create little to no unknowns
And the isomerization that s your target
your description of the process suggests you should not attempt this yet. If youâre unclear on the meaning of catalyst vs isomer, youâve got a lot of reading to do.
start with the definitions of Isomer & catalyst. use google.
if you canât define âisomerâ, how are you going to know if youâve made one? Do you have any idea what else you might make?
How are you planning on evaluating the success (or failure) of your isomeriztion reaction?without a way of figuring out what youâve made, all youâre doing is destroying CBD.
Folks with actual analytical equipment (HPLC, GC) are making stuff they canât identify.
were you just planning on âadding an isomer, heating, then huffing the results?â. please donât. you have no idea what youâre makingâŚ
if you can manage TLC and are doing this for your own edification, then by all means, but if you have no way of knowing what youâve made, I respectfully suggest you donât attempt it, because⌠YOU HAVE NO WAY OF KNOWING WHAT YOU MADE.
huffing it to see if it gets you high has been documented as dumb.
Yes I know, I have a lot to learn. Iâm new to this topic and I read another thread about isomerization and there sounds relatively easy. But now I know it isnât easy. and I donât want to make it when itâs not safe. First I build my SPD system and learn normal distillation without catalysts in my extract. I will read about isomerization in future and try it when Iâm 100% sure what I do.
it is relatively easy. BUT you need a way of figuring out what youâve made. without analytics, youâve got essentially zero clue what is going on. if youâve got the ability ($ and availability) to send your products out for third party testing, then you can make progressâŚ
My gripe with 3rd party labs is they seem to be staffed by fairly generic chemists who donât treat any one sample with any particular scrutiny or with any insight into what the sample actually is or could be - although they do fine at identifying the basic cannabinoids. I mean, how many labs have all the dienes, varins (or whatever chain), double bond isomers, acetylation products, hydrogenation products, and their acid counterparts? None, because thatâs prohibitively expensive and very commonly career analytic chemists lack broad synthetic insight. I will say, some third party labs are willing to add standards to their libraries at the request of a client.
That is to say, synthetic work however facile should be done by groups with at least one person on board who is proficient enough in analysis to do basic LC method development and has the wherewithal to either have the standards on-hand for all likely biproducts (something one should ponder heavily with any reaction, really) or to isolate impurities for NMR purposes and make internal standards if necessary.
Is there a guide to testing that could help point me in the right direction? I am going to be attempting the process and donât plan on huffing it to see what I got lol. I would really like to do in house analytics but this option seems quite spendy. Im hoping there are some cheap options to help me dial in the process then send to lab for actual batches intended for use. Any help is greatly appreciated.
@Mattsm Use @kcalabs. They are on the cutting edge of testing. They are accurate and professional for all cannabinoids (not just D8) compared to all other labs.
But now I know it isnât easy. and I donât want to make it when itâs not safe. First I build my SPD system and learn normal distillation without catalysts in my extract. I will read about isomerization in future and try it when Iâm 100% sure what I do.