I hope no one is making a base bath in a metal pot… saturated KOH or NaOH in iso or EtOH will dissolve glass and turn metals into explosive metal hydrides.
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Basically…not gonna lye
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Exactly why i didnt post it but someone felt the need to let the less educated help them kill themselves. and a lot of likers to support so
That persons corrections also were just reiterations from part of the full sop of the process from the same person DR Choi…
now that im realizing so i think they just used the keywords to find the process and post it themselves. You said we should edit dr choi’s to :
when it says here in is SOP “The base bath should be placed in a secondary container constructed of material such as HDPE Nalgene
and capable of containing the full bath volume in case the primary container fails. Do not store Base Bath
solutions in metal containers.”
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The olives are killing me.
If only I had pure water …
Now if NASA wanted clean and sterile items to go to Mars…what would they do?
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You edits/revisions of dr. chois base bath are reiterating the same words he used in his full SOP. A Ice bath is most def not necessary i drop 100 grams at a time in it and have never gotten close to boiling point. While it can be useful i really dont see the neccesity if you just do so slowly like most people do for any reaction. could it help u speed up the mixing with less risk yes but thats not really something that needs to be streamlined so slowly dissolving the KOH shouldnt be problematic.
@Ralf Would also like to hear the reasoning of why you think another stronger acid would be better for the process besides “its stronger.” Im all ears(eyes) if theres logic behind it but if strength is your goal theres plenty enough with KOH to get the job done(and less risks to the operators/people doing said cleaning.)
I had a chemists advise me of this one with 20+ years in the field that referred me to dr choi’s SOP im not the educated one who discovered this but was taught of it by people way more qualified than i and most of us, if they decided a more expensive acid was needed in a cleaning process there may be some reasoning to that. I dont know indefinitely but unless you have a PHD and decades of experience like them or some study/link to further prove your point im going to have to stick to their SOP’s
Also if your plastics are bulging/deforming during said process you likely didnt look up KOH/NAoHs effects on certain plastics. Some plastics have an A rating(can withstand the basic conditions for up to 6 months if i remember correctly) - a $20 tote from walmart with held the contents of base baths for 4+ months at a time before i dumped it due to it losing its efficency. some others will dissolve within the day. It goes back to the same thing as PVC/butane. and why we exclusively use high quality stianless/glass to process with butane to avoid such. And if you did search so and still resulted in that occuring you are most definitely mixing in to much at a time.
Using a dilute acid rinse as a neutralization makes sense. I assume it’s intended reduce glassware degradation. Care to share that SOP? The complete SOP from Dr. Choi in the link I shared doesn’t include an acid rinse, only a double water rinse.
The goal with NaOH isn’t to increase the base bath’s alkali concentration (strength). It’s to use an alkali of greater purity, which also has other positive attributes, including weaker exothermic reaction, less cost, and faster dissolution. The molar concentration of the alkali in the base bath would not change, where Dr. Choi’s SOPs call for ~1 M of KOH. However, when accounting for the typical purity of KOH (90%), the molarity becomes ~0.9 to ~0.96 M, depending upon the SOP used (see my other post for the two SOPs). I didn’t provide information on the NaOH concentration to replace KOH, only that NaOH is probably a better choice. I assumed that if someone followed Dr. Choi’s SOPs, they could calculate the required mass of NaOH per volume to achieve the same molarity as KOH (after accounting for purity). The difference in solution pH between KOH and NaOH at equal molarity would be minor.
An acetone rinse after a water rinse is common when cleaning lab glassware because it’s water soluble and highly polar, so it readily dissolves most organic compounds. The water rinse washes off the inorganic ions from the alkali hydroxides (e.g., K, Na, S, Cl, Fe, Ni, CO3, etc.). Then, the acetone rinse washes off residual organic material left after the base bath and water rinse.
Dr. Choi’s SOP allows the glassware to be oven dried 15-minutes after the acetone rinse and subsequent air drying.
Good idea to point out that the required glassware prewash before the base bath. Per Dr. Choi’s completed SOP (I would add that post detergent washing, a triple dH2O rinse would be ideal):
Pre-washing the soiled glassware
- All soiled glassware should be prewashed with appropriate solvent to get the glassware as clean as possible. Collect the solvent used to wash the glassware in a container and manage it as hazardous waste.
- Wash the glassware with detergent and then rinse with distilled water
I’m not sure to whom you are directing that post. But, if it’s to me, regarding my edit to this post, where I wrote, “Make sure you understand what you’re doing before using this method,” the “you” I was referring to wasn’t @cyclopath. The “you” referred to anyone reading who may not be familiar with this method (or working with strong alkalis). 
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Nice! I had no idea of so and its not something i was to interested in delving into so thanks very much for describing/ so.
It was directed to you tbh as it wouldve been to anyone else that publicly posted it as i really do think some people still wont realize the risks after reading so and may harm themselves instead of just doing normal glass cleaning even if it dried on and was a painful process.
I see you joined this site just a few months back so in all transparency verified consultants here have poured Acetonitrile from HPLC into water bottles confused it drank it… many other sketchy things have occured from people not following basic safety procedures if you delve deep enough into this site. More than appreciate the spoonful of information but yea thats my reasoning of not sharing anything to caustic/acidic or anything generally thatll put you in the ER if your lucky.
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Edit.
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Saving brain cells edit, lol.
Uhhh because you stated his SOP didnt say things it did? He mentioned HDPE containers when you stated the SOP didnt? Your talking about our egos but the text is above for you to see?
If thats how you choose to view it than so be it, i literally said what it was? if someone wanted to learn so i left enough key words there for them to do so themselves. i wasnt going to post that half ass sop you originalyl posted for many obvious reasons.
Yes and i thanked you for the knowledge, if me wanting to trust someone with a PhD over a person on the internet i have no idea about is negative than so be it, im negative. Ethos, Pathos Logos is something i learned and live by. Credibility is a huge determining factor in things THAT CAN KILL PEOPLE.
Yes this was intentional as stated…
i did notice and is why i asked for your reasoning, i said before you replied if you had some beyond it being a greater strength id adhear and guess what i did?
YOur ego got in the way here.
Exactly why you slowly add it so it doesnt occur?
i did nothing but explain how appreciative i was for the info and stated i wouldve replied the same way to anyone who linked the reply but you double backed and came here to pick a fight after i ackowledged what you stated cause it made sense? Your ego tripping buddy. I asked for a valid explanation because people with PHD’s had other recommendations, yours were beyond valid and logical so i didnt butt heads with you i liked and agreed with you?
Ralf…sorry if it seemed I was somehow “dragging’ you.
I wasn’t. I was joking Mamoris about olives soaked in Lye and
I made a joke with Cylcopath about the water solubilities of cannabinoic acids. ….There are at least 5 patents on methods of extracting Cannabis with NaOH, KOH, KCO3 and Ammonia…Water and Water Ethanol systems…well yes you can wash the Cannabinoic acid residues off your glass with N NaOH…
Look put all your glassware in a self cleaning oven…push the on button….forget the lye washes. That is just good advice.
Now that is for the Organics…and let us not go into the inorganics
…but if you have something inorganic left over that is not
Soluble in H20….as Marmoris has pointed out…proceed with caution.
Ralf…you’re doing ok. Forget about the lye.
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Trust but verify, if you think im not going to do so with caustic/acidic things or anything that can kill someone than you can go on about my ego, why dont we have dr.choi come in here and cry about your criticism of his SOP? Cause we did the same thing to you that you did to Dr. Choi all iasked for was reasoning? and if you think that first pdf you linked was HELPFUL IN ANY WAY YOU ARE BEYOND UNEDUCATED. That first SOP will severly harm the uneducated. as it doesnt state SHIT about JACK SHIT of the process besides mixing it slowly. No safety procedures no explanations of how caustic the solution is many other things.
YOu clearly havn’t been on this site long enough. Weve had people deemed verified consultants THAT DRANK Acetonitrile AND MANY worse things AS STATED. If you trust those people with caustic/acidic washes than god damn you are delusional. Theres having faith in people and theres watching darwinism occur and giving them more reasons to prove his theory.
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Lmmfao. Who the fuck drank acetonitrile?
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People Future4200 deemed as verified consultants at a point and had them going around teaching others for $$$$
ask @Kingofthekush420 he was apart of the hemp facility that had 4 “consultants” working there that almost died several times got the facility closed down and more.
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I don’t plan to use the base bath cleaning method. I only wrote that in case other people want to give it a try. I’m planning to use what you wrote a few days ago:
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While very unfortuante this is one of the people that worked at that hemp facility, apparently he went back in to save some others and never came out very heroic indeed. but yet another situation of WHY I DONT SHARE THINGS THAT CAN KILL PEOPLE HERE
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Futures favorite chemist
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For some reason they were using water bottles for the mobile phases on the hplc
They just so happened to have the same brand of water bottles around (to drink) and somehow the homie ended up drinking some luckily he didn’t swallow he spit it out
He was rushed to the small local hospital where they didn’t know wtf to do and he even told them what he needed because dude knew his shit when it came to poisonings with certain solvents
They ended up flying him on a helicopter to the nearest big hospital a few hours away
I wasn’t actually there when this happened it was right before I came on
Lesson : don’t use water bottles for waste or the mobile phase on an hplc
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And don’t have drinks for food in the lab. Saftey 101.
OSHA 29 CFR 1910.141(g)(2) Eating and Drinking Areas
No employee shall be allowed to consume food or beverages in a toilet room nor in any area exposed to a toxic material.
For:Safety Training: Let's have a Fire Drill @Sidco_Cat
…and depending upon who was last in the “toilet room,” that could be considered a location of toxic material, too 
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