don’t tell me how to live *chops rail of DMSO
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I can confirm that by using by using MCT, glycerol monosterate, gum acacia and polysorbate 80 you can use a Polytron homgenizer to create an emulsion that is translucent and when added to water as a beverage base, the water remains clear. I was planning to use the Q Naturale quillaja extract, but it has gone missing from my lab. Hopefully nobody is trying to get high with it. I need to refine the formula and bump up the CBD until the breaking point. Stay tuned…
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This is the soluble CBD in a prototype beverage base. Notice the purple color. This is from the aqueous phase having water soluble blue food coloring and the lipid phase having red food color. This sample has been sitting 24 hrs. The smaller bottle on the left is distilled water with an eye dropper of base. It has passed the initial “ring test”
This 125 ml sample has 37.5 mg of CBD. It’s hard to judge turbidity due to the colorants, but would be satisfactory for anything other than “enhanced water” type products.
More next week…
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Look into the p450 enzyme. Doesn’t process well with people on medications that can’t be taken with grapefruit.
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Clean Label CBD in water emulsion
Polytron PT 10-35 GT Homogenizer
Near monodisperse emulsion, 1 micron particle size
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Ethanol? Care to share how you did this?
I will have a more complete write up once I am done with my experiments. This sample is only 1% CBD. I will be running 5% later today. [Redacted due to possible patents issues]. I am using a Polytron homogenizer with a 20 mm probe at 30,000 rpm, and then an ultrafine probe at 12,000 rpm.
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5% processed as well as the 1%. As the mixture was thicker due to 5x the quantity of gum, it heated up faster from the shear forces. [Redacted due to potential patent issues] The mixture is also pasteurized at this point as well. Now comes the hard part…waiting to see if it passes the shelf life test.
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Is there any remaining ETOH in the final mix?
I am sending samples out for analysis. I may be limited in how much more I can share on this project. Will advise.
I have been advised that I may be posting ideas that have already been patented. The USPTO has issued some very broad patents in the cannabis field. For example, dissolving CBD in ETOH and adding it to vodka is protected by US Patent 10,085,965
Sick patents galore keep up the good work
Great results Sheerguy. How long have you let the emulsions stand at room temp to test for creaming and separation? What are you using for a preservative? The preservative is proving to be my biggest hurdle right now. Clean labelnis also my requirement. I was hooing that the claimed anti bacterial effects of CBD and Quillaja wwould be enough but after 2 months I’m showing black spots of growth on the glass around the top of the emulsion.
Research claims that without a preservative any water containing emulsion will last max 5 days in the fridge.
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I am not seeing any creaming. Nor any ringing. 1 week and counting. The process I use heats the sample into the pasteurization range, so it could conceivably be bottled hot and have an extended shelf life.
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Is anyone using filtration for sterilization? Is anyone mixing the CBD into ethanol, doing the sonication blending with the surfactants, filtering and then using a rotovap to remove the ethanol?
One thing to consider is that ALL of your encapsulated CBD must be smaller that the filter pore size or you will be filtering it out, along with any pathogens. Do you have access to a particle size analyzer? You would need to look at the particle size distribution.
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We would be doing it either with a microscope or would have it analyzed by a different lab. We certainly are keeping that in mind.
This is an interesting idea. Care to discuss more? How often to degum…
I would advise sending it out. However, if at 1000x magnification you don’t see any particles, you can assume that they are all below 250 nm, which is the smallest size an optical microscope can discern, for the same reason these emulsions are clear, the particles being smaller than the wavelengths of visible light.
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