First things first, you will want to have a good analytical chemist to consult with. I’m a synthetic organic chemist so I used these but never had to maintain one or do any analytical work. Is my SM gone? Is my product there? Things will go wrong and usually no one in the industry has a service plan. I’m in the process of replacing all the seals and inlet. It’s not for kids but easier than HPLC maintenance (imo). There are plenty of videos and write-ups to help.
We run a GC-FID for oil. They will resolve d8 from d9 but my method uses hydrogen as a carrier gas (for now). We used restek standards to create a calibration curve but I never liked the results. I was told to go to an auto-sampler. I’m going to try again, using hot injection technique. Then I’ll but an auto-sampler. No one has mentioned using external or internal standards which I assume they are using if they are hand injecting. calibration curve. I use the best methanol and filter every sample, probably overkill but whatever. That’s all I can think of.
Sounds like we have knowledgeable people on this forum. I love this place.