Panakeia CBG GMO?

Does anyone have more information on the Panakeia CBG strain developed in Spain? It’s being released by Front Range Biosciences and Tesoro in the US. I heard they modified the DNA to inhibit the synthase of thc, thus guaranteeing 0% thc. Doing this also removed all terpenes. Is it the first genetically modified hemp to hit the market?


Reach out to them and see if they can make me some cannabis that grows with no leaves. I been dreaming this strain up for 20+ years. Super terpy with 50%+ THC would be nice also but not a deal breaker if they can’t swing it. :wink:


I’lll order the same but make it a large THCV with a side of mold resistance


All of your information is correct. Front Range Bio will be supplying clones from tissue culture while Tesoro is licensed to supply the seed.

Clones will be available from FRB’s “clean stock program” by end of March but pre-orders are accepted now. All clones sold will be registered with the purchasing states Dept. of Agriculture.
18% CBG with 0.00% THCa

And you are correct about the terpene profile. This cultivar is specific for the industrial production of CBG.


Thanks for the confirmation. I couldn’t find anything online about the dna modification, just heard it from a friend. I guess in the US, we don’t have to label GMO’s and it’s not really that great for marketing. I wonder what the community as a whole will think when word gets out.

I’m not too familiar with CRISPR or DNA editing, but I’m curious of what we’ll see next. Is it possible to increase resin content to 50% or reduce leaf production?

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Its definitely interesting to see where things are headed. They are synthesizing CBDa and THCa now. And growing THC and CBD from yeast and algae.

I just dont understand why we cant enjoy this plant and the compounds it produces naturally.
We always have to call dibs and monetize everything


Do you know of anyway someone could secure a small amount of these beans for personal research?

The seeds will be distributed by Tesoro and im not sure what their MOQ is.

I am working with Front Range Bio to supply clones. Lets stay in contact and I will keep you in the loop on any orders that we might be able to attach you to.

This is a cultivar that they prohibit cloning, however. And because it is patented, they have every intention to enforce that.

I’ve been unable to confirm the GMO origin. do you have hard data on that?

if it is patented, then there should be a patent that can be explored for details.
you don’t happen to have pointers to that primary literature do you?

I did find a naturally occurring variant published in 1987

As always, it is only words on paper until proven in the usa, by someone you know. buyer beware. Why anyone would buy words on paper vs oregoncbd cbg that’s proven with thousands of acres harvested, for less money, makes me question human intelligence.

I’ve tested various CBG cultivars the last months, pretty new, various origins (Netherlands, Switzerland, Italy) ranging from 2 to 15%, and with various thc:cbd profiles behind the main cbg, some being compliant (but no 0.00 thc)… most of this seems pure breeding to me.

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Let me see what info I can get from FRB regarding the patent/ licensing agreement, if any.
Ive been spewing the information I was given without looking deeper into the IP.

Regarding GMO, its been described to me as gene “editing”
My interpretation was that meant genetically modified. But since there is no combining of DNA, I suppose its not technically GMO.

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That’s probably close enough…

Although if the specific edit is patented, the details should be available, and I’m terminally curious.

Edit: gmo == genetically modified organism. An edit to a specific gene is 100% a genetic modification.

Ionizing radiation on the other hand, while it definitely modifies genes, is too blunt of an instrument to qualify as “genetic modification” imo.

we flailed around with a sledgehammer and got this new thing…


Apologies if I missed it, but have they indicated price per seed or clone yet?

On the breeder’s end I remember one being quoted 6-8% of gross revenue of Front Range’s tissue culture sales, not sure if that’s consistent though.

The patent will prevent the sale of clones. IP law is civil. 3x illegitimate profits is common as damages. But my guess would be, regardless of a material transfer agreement, those genetics are going to escape captivity in about an hour as soon as they are publicly sold. Then the patent owner has to be able to track down all the people selling it under a different name, and sue them individually.


this distinction is applicable to “transgenic” which == “we transferred genetic material”.

All transgenics are GMO.
Not all GMO are transgenic (now that we have edit capabilities).

I can see some folks performing such edits trying to convince the public that editing a gene in-situ is less scary that popping in a gene found elsewhere, or constructed de-novo in the lab…there may even be some validity to that argument.

I’m of the opinion that we were handed tinker toys…so lets see WTF we can build.


I agree.

All information that has been released is very vague. Other than they found a way to block thca-synthase.

Isnt that how most major discoveries are made? Attempt to solve one problem and discover something massively different…like viagra haha

No worries.

Clones will be sold for $6-$8 based on quantity.
Im not sure about seeds as that is through Tesoro Genetics.

If there is enough interest, I can set up a conference call or webinar with FRB to answer any questions as well.

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It would suck if pollen from that stuff ruins all weed before freedom reaches the masses.


as a knockout, this particular modification should be recessive.
so it would only ruin some of the weed…

and even then, only if you let it have sex AGAIN.

edit: knocking down a synthase may actually give a semi-dominant phene. so yeah, turning all the weed into weak sauce is a conceptual worst case.