Stability of Psilocybin and Analogs.pdf (930.5 KB)
This paper is pretty informative but I can confirm that freeze drying isn’t the way. Even at moderate temps like -10 C it will certainly completely dephosphorylate psilocybin to psilocin. Using an off the shelf dehydrator preserves the psilocybin almost completely.
As far as homogeneity, if you powderize it’s helpful to sieve it to a uniform size and then mix otherwise there will still be higher concentration pockets and settling.
I prefer extraction to have large lots with an ensured homogenous potency, but I agree drying and grinding to a powder is very simple and effective for home use that is in a timely fashion. For storage though, extraction is far better because the enzymes will degrade even dry biomass. I have independently verified that this paper is pretty accurate from samples I’ve tested: about 50% loss after a month.