@Distillforeal There is actually a lot of research on GMOs. Here is a summary of a decade of EU funded research: https://ec.europa.eu/research/biosociety/pdf/a_decade_of_eu-funded_gmo_research.pdf
Also, I think this is a different type of GMO than most people worry about. CBD is CBD, just as THC is THC. Doesn’t really matter where it came from as long as it has the same number and arrangement of atoms and is of sufficient purity.
I personally don’t have a problem with GMOs. I think producing cannabinoids destined for medicine (i.e. Epidiolex) can be produced in a more environmentally friendly and safer manner. I mean, look at the way many extracts are produced. People are winterizing in methanol, a variety of hydrocarbons are regularly used, and I’ve seen patents for THCa crystallization that utilize columns with DCM… this is potentially a way to circumvent all of that. There are massive energy inputs that go into producing extracts by current standards too - in CO, like 10% of our energy usage is for cannabis production.
We don’t really know much about the “entourage” effect beyond anecdote (and I personally FEEL a difference, but that doesn’t hold up to the rigor of peer review); however, I think talking about the whole plant vs. isolated compounds (or oranges vs. vitamin c) for this discussion is a bit moot because it isn’t an apples to apples comparison. I think there will always be a place for flower and flower derived products, but we shouldn’t demonize a new process that could make what we do safer and greener until we learn more about it!