You will need a lot of dextrin to make that nano oil stay in powder form, that’s for sure.
Has anybody first hand experience of the water solubility of beta-CD?
The numbers in scientific papers vary from 18.5mg/ml to 120mg/ml.
Based on that paper, I need a ratio of 7g beta-CD per 1g of cannabinoids.
I am working on project to get a THC emulsion with 10mg/ml.
If the solubility of beta-CD is 18.5mg/ml, I am only able to make 2.6mg/ml solution which is too low for my task. But if it is 120 mg/ml, I am able to reach my goal of 10mg/ml.
Can you use beta cyclodextrins? I thought I read somewhere they weren’t allowed in food products
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/beta-cyclodextrin
" A maximal level of β-cyclodextrin of 5 mg kg-1 per day in foods is recommended by the Joint FAO/WHO Expert Committee on Food Additives (JECFA)"
“Based on animal studies and human experience, harmful effects of CDs are not to be expected at doses below 20 mg/kg/day.”
If 20mg/kg/day is the limit, this would be high enough to create a product with a daily dosage of 200mg THC and call it “safe to consume”. If 1:7 is the correct ratio.
I am more concerned about health risks of daily/regular consumbtion of polysorbats and other emulsifiers.
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They’re pre digested
Just like Risotto
That assumes digestion has stopped. How is it stopped? As long as particles collide they have the potential of continued aggregation of size in the absence of something to prevent it.
In actuality digestion slows but likely continues in perpetuity.