In an attempt to set the record straight I propose we as a community could try to get
A standerized sop for the isomerization of cbd to Thc D8
What I think should be possible to be done by us themembers is have D8 made by the several paths known to us and have these analyzed by hopefully @iontrap and @kcalabs
To start this endeavor I propose a poll
To get an understanding of the sop used at this moment by the members of this forum
To get a picture off wich sop should be chosen as starting point of this quest to clean ( non poison containing D8 )
Please Vote on your method used right now
Lets make a sample of the most used sop
Let these samples be analyzed let the outcome of these samples be opensourced
And let’s move from there
I am sure folks like @anon32743824 @Kingofthekush420@densone. And all the other masters of their trade are willing to do one sample run of a catalyst and have it analysed by dooing this we will all benefit
The professional the amateurs and the consumer we can get this done and there is absolutely nothing holding us back
Thank you sir @Curious_Roberto
Guy s have no shame if we want to make good meds we might have start back from scratch
But will figure out the best rxn and cleanup for this
Every singel obstical on this path can be solved with all these great minds here
Whether it s cleaning solvent prior to use or catalyst , reaction conditions and the works
We can and will nail this
My vote, if we’re going for a safe, defined, product, is always going to be “evolve an enzyme”.
While I can’t come up with a selection scheme off the top of my head(making D8 means you live, not means you die), I believe that I can come up with a decent screening protocol.
I’d start with thca synthase in e.coil. Mutagenize via pcr, clone into lamda. Plate on media with CBD. Perform plaque lifts, and stain with fast blue.
Someone smarter than me might look long and hard at thca & CBD synthase, and make some informed guesses…
In all seriousness this can t be that hard to get right
I know we are only the tip of the iceberg in isomerization land but we must and should be concerned off what we make
If he’s not gunna try the proven safe product then he shouldn’t really have a say in this since it’s just obviously a biased opinion that won’t change no matter what steps are taken
That’s all I’m gunna say about him in this thread. Let the science to the talking not biased opinion