It’s funny you say that. I’ve heard that gabapentin got rescheduled because it’s abused in combination with opioids.
I honestly wish I was prescribed Valium for sleeping. Every time I couldn’t sleep at the E. R. I was given Valium and I would laugh myself to sleep. Every time I would laugh myself to sleep the nurses would think it’s cute.
Regardless of ANY substance, nothing replaces a balanced life, have work to do, a home to rest in, food in your belly, and the knowledge it will all be alright the next day, will do better, than any replacement therapy.
Some people need extrinsic substance for verified imbalances, that is the only tangible use. Everything else is taking a stab at it.
Weed doesn’t “fix” the underlying issue. But it sure helps slow one down enough in hopes that they can find relief from it. But there’s still an issue you need relief from.
Weed induces GABA btw. Its actually the synaptic response to CB1 and CB2 semi agonists and agonists, also why full agonists at high doses cause seizures.
Anatomy and physiology, biology, Chem, give you a great foundational knowledge.
The only reason I know of this interaction (honestly) is a good friend of mine is a nueroscientist (God I loved having conversations with him) and we had a session over interactions, he showed me the paper, I just never received a copy sadly…