HHCA did crystallize readily btw
https://www.instagram.com/p/Bp-8IAMD7tO/?igshid=k3tfa7ir8wjt
HHCA did crystallize readily btw
https://www.instagram.com/p/Bp-8IAMD7tO/?igshid=k3tfa7ir8wjt
Hydrogenated(H2) Cbd bares a resemblance to ketamine and itās analogues if you squint just right and add an amine. Really seems like many of the substitutions are just reversed.
Have heard 6-CBD had similar ketamine-esque effects like you describe.
Are you saying ketamine is a cannabinoid???
Not at all, itās kind of similar but still very different structurally.
Just the second time Iāve heard of CBD analogues having effects that the users compared to ketamine.
If you remove all the substitutions, your left with the same 1-phenyl-cyclohexane backbone, but thatās where the similarities end
But do the similarities really end there???
Havenāt read the article yet but looks interestingā¦ Maybe they are more related than anyone thought???
And
Well, Iāll be damned @broken_glassware @Psilisophical
holy shit, this is awesome @broken_glassware good eye.
@Dabatronicus @anon93688
So you guys made the hcbd? id love to get my hands on some more.
@Psilisophical I did not try the H2-CBD he produced or anybodies for that matter. Very interested in the reduced cyclohexene like you tried more though and the fully reduced H4 analogue as well.
@anon93688 Really be cool to make and test the 3-methylamino and 3-piperidine analogues (aryl bond at the cyclohexane, Cbd numbering is weird). Donāt have any access to a real database to search the molecule. Iāve tried various naming schemes and havenāt found anything on google scholar
Would be cool to try with both Cbd and the hydrogenated analogues, maybe work up from there with other strategic substitutions to compare the structure activity relationships of both.
It would also be cool to slap a pentyl or dimethylheptyl tail on ketamine
Are you wanting HHC or H2CBD?
Draw these in the Element app and send them to me. Iāll start looking for a way to make them.
App wasnāt working great so hand drawn
^^The 3-methylamino-H2-CBD analogue
Rough idea of H2-substitutions to explore the small series. (B) is piperidine
You could also substitute the Alkene for a carbonyl and/or add a chlorine meta to the hydroxyl to further explore the SAR between the two compounds(ketamine and CBD for those not following)
These are obv. not all direct additions and may require different starting compounds to work up.
Yo I already know how I am going to access these.
Seems like something that could be turned into paper or two.
Publications are political and I donāt want to be involved with that crap. Patents sure.
h2cbd. the hhc as well but the h2cbd is much more peculiar in my mind. not to mention its acetate ester
i misunderstood you before. it was the fully reduced analogue.
Also, I have heard of co-encapsulations with piperidine, but never actual chemical bonding. that would be quite fascinating
@Psilisophical send me your email and I can get you the procedure for H2CBD.
Edit: included tag
The piperidine analogue would be the equivalent of the classical ketamine relative, PCP*. Avoided mentioning it due to stigma.
Personally, these compounds are intriguing academically, but shouldnāt be tried in humans without extreme care.
Itās unlikely they are even active but it would be cool to see, atleast in animal models
*Just realized why itās called PCP, Phencyclidine never made sense. Phenylcyclohexane piperidine however, makes all the sense
same needed; if you will .
Good luck, considering he hasnāt been online for over 20 months