2.25 g citric acid and 1 g CBD were dissolved in 15 ml anhydrous ethanol.
Refluxed at 100°C for 16 hours
The solution is neutralized with 2.94 g sodium bicarbonate dissolved in water.
When neutralized, add water until an oil-like substance floats to the surface.
Add hexane to dissolve the oil in the organic layer.
Wash the organic layer several times with dH2O.
What is this?
Should I distill it and test it?
Start with reading about the alkaline beam test in the search bar. That will let you know if you have CBD remaining. As far as byproducts, only a GC will tell you that.
Anhydrous ethanol refluxed at 100C ???
Lol didn’t catch that. Curious what else might be off
Anhydrous ethanol boiling point is 78.5 C
How is this anhydrous ethanol made\bought and treated ?
Anhydrous ethanol is a very difficult solvent to make /work with
Your most likely working with 96% ethanol 4% water azeotrope mixture Wich is common
If your aim is high thcD8 it s fine if a high thc D9 it s not
As for citric acid solubility in anhydrous ethanol
It is
In my environment, anhydrous ethanol is readily available.
Considering heat loss, I set the temperature of the stirrer’s hot plate to 100°C.
I would like to try a reaction with anhydrous ethanol + 35% HCL, what is the best time and concentration to use?
I am thinking of
Ethanol : 30g
HCL : 0.5g
CBD : 5g
In other words, dissolve 5g of CBD in about 0.5% HCl ethanol solution.
How about refluxing this for 2 hours to verify?
Doubt it ! Cheapest I have found in Europe
Is 232€ per liter with still ppb water content
As for hcl the gas ? Or dissolved in water
Might help if you tell me what you try to achieve
And what you want to use it for
Makes things a lot easier
I understand the aim is thc but 8 or 9 ?
At what scale what equipment is available ?
HCL is 35% hydrate.
My goal is to isomerize as many percentages as possible.
Either 8 or 9 is fine.
Ideally, 8/9 should total 90%.
In my environment, p-tsa is a bit difficult to obtain.
Basic beakers and flasks, separating funnel, condenser
Heat magnetic stirrers
Rotary evaporator
And SPD if I decide to get one.
Ethanol on phosforic acid
Dry the ethanol with molecular sieves 3A
200 gr per liter
Take phosforic acid and dry it if all you are able to get is 85% in a normal oven until 15 %of it s weight has evaporated oven temp 110C
Make sure you place the phosforic in the middel of oven not on the botom where the heating element is
Link to the simplest alkaline beam write up.
Distillation under the deepest vac you can attain will probably be preferable to roto once you start scaling up
What is this?
Advice
It s a basic sop for cbd> thc conversion
Of all sop available this is the cleanest
In numbers 99% visible on a gc is very common
Color stays nice without much effort
Yes ethanol 96% is expensive but this works
Thank you very much.
But in my country anhydrous ethanol is cheap.
A 500 ml of 99.5 vol% anhydrous ethanol costs about $10. You can buy it at pharmacies.
@Roguelab Why is anhydrous ethanol so expensive in Europe?
Why don’t folks drink it?
(Some governments might achieve that with additives…)
I would expect this approach
Do you drink ethanol???
Maybe people in my country don’t like alcohol lol.
This is the price for reagent grade anhydrous ethanol.
About $100 for a 3L.
Does the phosphoric acid in this case need to be anhydrous?
