This is the most fucked up collection of misrepresentations I have ever run across. (In the form of questions.)
Resulting in hundreds of fuckuped answers.
Ending up being dominated by people who like to put their fingers up their ass.
None here knows whether “how to weed” is a troll or not.
He mentioned he got his idea “often discussed on Reddit”… and decided to bring that shit here…for a waste of time.
Give it up…
That wasn’t directed directly at you, that was referencing the 200+ replies without a clear answer still. If you took that personally that’s not my fault.
I just don’t want to continue arguing with you about nothing, prior we were having a discussion but now you seem to just try to be making personal attacks and jabs rather than have a discussion about the topic at hand.
What is bullshit is there there is no evidence that what you’re saying has worked on someone, and that’s a lot of shit to do with no proof. I was expecting someone with my issue to come and post what worked for them, not people who think they have an answer that hasn’t been tested, that’s what I mean by bullshit. I don’t mean to undermine your patent or whatever you’re offended by.
Pretty sure you’re not gonna find hydroxy THCs in Canada anytime soon - I kinda doubt health Canada would let that fly. My bet is that anyone (3chi) making any of the hydroxy THCs now or anytime soon is doing so synthetically - Cayman certainly is approaching any of this stuff synthetically. But they also have the luxury of making a gram, running chromatography, and selling it’s milligram-by-milligram for hundreds of dollars.
Do you have a working hypothesis for what the issue is?
Yes? What is it?
No? Sequence data may help.
You think it’s your liver? (Or others do)
Have you explored that?
How could you explore that?
You won’t explore that because it’s bullshit…
Sadly they sell theirs in methanol and not straight or I would try that.
Just wanted to give head nod at someone calling cayman chem out on their BS. By rich people for rich people only company and of course is the only RC company left standing these days that’s remotely legit. Rich people bs.
Hope they choke and die on their greed over there =D
I don’t care why it doesn’t work, or how it doesn’t work, knowing all the knowledge in the world wouldn’t change the fact that… it doesn’t work.
We don’t have solutions for “reason x vs reason y” that it doesn’t work, so who cares.
It seems we either have no solutions, or one that would work for all methods. So once again, why bother finding out why it doesn’t work on me?
I’m pretty bitter towards food in general with my eating problems, but thank goodness edibles work lmao
Yeah you also probably would spend thousands of dollars just to get enough milligrams to feel anything.
I have heard this “edibles don’t work on me” from a select few people before. One of which I gave 500mg/mL tinctures of d8/d9THC at some point and even then they described needing to take like…200mg doses just to get buzzing. Same person gets very stoned from smoking and vaping weed in modest quantities. So at least, I’ve maybe observed an example of what you’re describing.
Totally anecdotal - but I once knew a guy with a native American heritage who was dramatically affected by alcohol…like totally sloshed from 2-3 5% cans of beer. He claimed it was something to do with genetics. To bring it back to THC edibles, the only two people I knew who described edibles not working were from Nordic countries (Norway, Sweden, Finland). That is to say, it’s not crazy to think there could be a genetic component.
Mixing thc with liver extract?
Or adding back the missing enzyme?
You’re not willing to throw $500 at figuring out which enzyme you’re missing. you’re correct adding it back without that data is “bullshit”.
the claim that there is zero data that mixing thc with liver extracts will metabolize THC to 11-hydroxy is also bullshit.
For in vitro analysis, pooled human S9 liver fraction was incubated with (−)-Δ-9-THC. Resulting metabolites were detected by high-performance liquid chromatography system
Why not just buy 11 hydroxy and skip this? Ah skipped over Canada
I wasn’t really calling them out. They sell a precision product used for calibrating instruments, it’s not mean to be a good deal on whatever compound your buying - it’s just supposed to be exactly the molecule they say it is, exactly as pure as they say it is, and at nearly the exact concentration in solution they say it is.
It’s also pretty much by necessity that they work totally synthetically. First of all, it allows them to make damn near anything. Second of all, it means they can make whatever compound they want consistently and without disruption to their supply. It’s potentially more problematic for them to make HHC standards from cheap/naturally occuring CBD (CBD>THC>HHC) than to make it totally synthetically from reliably pure non-cannabinoid starting materials. The CBD may have residuals “stuff” from its natural origin that makes an HHC standard derived from it difficult to certify as a CRM.
I agree standards are expensive, but so is the quality control that goes into making sure the standards provided to testing labs always work.
Because if you don’t know how it’s fucking broken how in the fuck are you gonna fix it?!?
Especially if you won’t try “mix D9 with liver enzymes”
And now it’s probably time for me to wander away, because after suggesting it for three years I’m fucking bored.
Because he doesn’t believe anyone is actually selling it, near as I can tell…
I agree that it’s not on 3Chi’s website, but there are certainly a number of articles suggesting they’re making it.
With a ref standard from cayman one could even verify before eating/huffing/sticking it up your damn ass.
I disagree. I think it’s possible, especially at their scale and level of production, to produce- en-masse- extremely cheap/accessible, pure chemicals. This is a big pharma move to keep chemistry out of the hands of the poor and also further enable the drug war and myramid of other “symptoms” that benefit the rich and hurt the poor that branch from that.
There should be no underground RC sites. Which are all scams now anyway. It should be a bunch of well known labs with practices and looks just like cayman chem. Only their meds should be 100000000x cheaper, if a underground RC lab can produce Diclazapam at high purity for 20/$ for 30mgs or so, then cayman tech can certainly do it even cheaper and better.(I think they have diclaz listed at like 300 something bucks or 170 something bucks A/MG rn… lol) The money they would make to if they changed their ways would be stupid, for lack of better wording. But they make even more “stupid” money by practicing the way they do and manipulating entire populations and industries and keeping chemistry exclusive only to big money that can afford these chemicals. And say, if a rich person wanted a RC like diclaz cause their having bad anxiety or insomnia and getting prescribed valium these days is impossible, well… they wipe their ass with 10k every morning, it’s literally not even a thought for them to drop that on a “script” of 170$/mg Diclaz, but for a poor person who actually medically needs it, and DEFF doesn’t have access to the good meds(like a rich person prob does anyway. private insurance opens all the doors) they need to mortgage their house, lol. Guess I’m getting off topic again here tho… Sorry OP XP I can rant about stuff like this forever. Hate companies like cayman… =/
Besides it being in methanol they sell 1ml for about 179 it seems pretty affordable, if anyone else has a clean source let me know…
So I was right, no has ever one it for real, in vitro testing doesn’t mean it works in real life…
You’ve suggested it but never done it yourself, that’s not a suggestion that’s a bullshit pipe dream.
wrong.
we took some liver, we added some D9, it made 11-hydroxy.
right there. in the test tube. the HPLC told us so.
all you do is repeat AND EAT (which is the only part they didn’t do).
That’s all I wanted to hear, was that so hard to say? Jeeze bro.
I was calling all of this bullshit because it seemed no one actually tried it themselves and were all just going on speculation or other peoples work…
2020 Great reference…missed it…complicated ion spray data.
@HowToWeed Look here…buy it
There is a standard in vitro assay with Human liver S9 fraction (pooled—number of donors 34) was purchased from Thermo Fisher Scientific (Schwerte, Germany all outlined to get your 11-OH going. 34 human donors gives your a decent chance for retroviruses….lol. Btw if one intends to bioassay resulting soup….
Personally I’m going to stick with the lipid lymphatic route …and the video of the woman chemist (who is she) and two grown men on the kitchen floor, she saying :” I told them not to eat two brownies.” YouTube land somewhere.