The spectrum of effects produced with single doses of N,N-dimethyltryptamine (DMT) in 6 nontolerant human subjects resembled those produced with lysergic acid diethylamide (LSD). Either drug produced an elevation in systolic blood pressure, a decrease in the threshold for the kneejerk, pupillary dilatation, and a mental response characterized by anxiety, perceptual distortions and hallucinations. The onset and duration of action was shorter with DMT (0.5 mg/kg) as compared to LSD (1.5 mcg/kg), but the maximum intensity of effects with respect to each parameter was equivalent for both drugs.
Following the chronic administration of LSD only a mild degree of cross tolerance to the mental response could be demonstrated with DMT (0.5 mg/kg) in subjects highly tolerant to the pupillary, kneejerk, and mental effects of LSD (3.0 mcg/kg).
It is inferred that the site or mechanism which is altered during LSD tolerance is not one which is primarily concerned with the action of DMT.
Another positive beautiful thing about cannabis for me: no dream memory I dab and it’s gone. Magnesium and 5htp were things I took after a night on mdma. I do remember the positive impact and should look back into it.
There are nights where I wish I could dream but I hate how I’m nightmare prone and mine are so fucked up I wake up in tears sometimes. I wake up giving the moaning screams… Full body sweat to the point where a full 24×24 pillow is soaked through.
I also have muscle spasms from tmj and my back and I have a hard time staying asleep because the sound of my breathing pisses me off once I wake up. … There’s no winning but I take anything I get for sleep because it’s good enough for me. Sleep is something that makes me feel like it’s a concept that I can’t grasp well…
A buddy of mine has a story of him ~2011, smoking ~200mg JWH isolate off foil while he was on mushies. said it was like a lightning bolt that hit him right in the head.
He went to the emergency room in a panic. They obviously had no idea what to do for him and ended up giving him a bunch of xanax to come down lol
I think that was the last time he smoked spice lol
I smoked K2 right after smoking Cannabis in the public gardens with a group of people I had no idea who they were, a really good friend at the time was with me and thank goodness because I felt like I was having a sideways heart attack with the ground looking like it was exploding with every step. Not ripples but like imagine a giant creature stepping into the ground and you seeing just holes and they’re bringing up rocks.
I was a very wrekless and irresponsible human being but I knew not to do anything like that again and I told everyone after “Fuck K2, unless you wanna die, feel crazy or both.”
The heart attack feeling and feeling like I was gonna die is the most memorable about that. I think to myself when I think about that day, that I was seeing things because my heart was palpitating the entire time and that I was potentially just dieing.