Just as something anecdotal. I tried this reaction in a couple different ways; thought I’d be inventive and stray from an SOP.
I’m not a chemist, and despite doing a pretty decent job of argon blanketing and keeping proper vacuum…
The reaction got fucked up. Mystery peaks ran rampant, there was all sorts of side reactions, and I figured I’d try a dab of the distillate …
My lungs completely closed up for 20-30 seconds, and for a good panicked half minute I was wondering if I was ever going to breathe again. I then had the worst cough of life for 5-6 hours and my tongue and teeth felt weird for a good week afterwards.
I turfed the run; but if theres someone inexperienced on here with less scruples would be unwilling to throw away a mistake. This shit can be dangerous, especially without tight parameters and proper equipment.
I’m going to go back to the SOP, and add in some chromatography afterwards.