Nothing i use was designed for it
But i mean Nothing 
So in my language it means go for it
Pilowcases for biomass pandaās. 
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However, synthesis of 3aās to a more specific binding affinity is piquing my interestā¦
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Ion exchange resins
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Thatās a great one, Iāve had a lot of great luck with some of the older Dowex products that have been replaced by several other new products. Just seeing the number of different fractions I can pull based on pH and polarity is amazing. Iām currently collecting fractions this way and rotovapping them down for analysis. One of my current pet projects.
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This is like a fun homework assignment that might lead to nowhere.
https://twin.sci-hub.se/6830/61fe19c5d30adba1e4ade0b8ba6204f0/williams2010.pdf
3a mol ā my guess is the resin is the whole situationā¦and no one knows what that resin is yet.
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XAD is baller for seperation between the pentyls and the propylsā¦
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Fun! how are you quantifying? I wonder if I could set something up with the fraction finder to try something like that out? Ill have to poke around for some medias. What solvents you using? I wish i was associated with a larger outfit to be able to afford cool research stuffā¦ all these extra curricular purchases really leave me in the poā house!
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This tech (bids) would be awesome to implement but with current pricing of all fancy raisins it could be projected as the āoverkill priceā to implement on the big scale ā¦
For the people on this forum who was laze or busy to do the R&D on this - simple SOP for color removal ,thc CBD separation and surly for encourage to start the new topic in here.
Mix your crude or distillate with heptane 1:1 ( for crude soline wash is needed)
Get 3A zeolite (in jar for the simplicity) and wash it with fresh heptane ( drain solvent out)
Combine your mixture and zeolite (fill till zeolite fully suspended)
Wait few hours .
Filter ( coffee filter is fine for this step)
Liquid portion will go back for the re run (if CBD/thc separation is desired)
Zeolite in you filtration funnel now loaded with the goodies.
Prepare second filtration funnel for color CRC STYLE 1ā-3ā of b80 will work, put loaded zeolite on top
Run fresh Heptane ( acid spiked if not decarb crude was used) to wash zeolite. Collected heptane would be almost white and it will wash out only 50%-60% of all available goodies but zeolite will hold up the thc molecules a little better so with this method it is easy to bring down % of thc in oil drastically
My personal record from almost 8% down to 1.2%
Donāt forget zeolite still loaded with cannabinoids needs to be washed with different solvent (toluene)
Is the second solvent of choice to remove cannabinoids but not the garbage.
This SOP was for the 1st grade students ā¦ lol
For the pros:
3A is 0.3 nm al the bulky molecules canāt feet
Zeolite exist in the form of powder (column loading)
Zeolite based ion exchange resin will give have a force to hold molecules (thc/CBD separation)
Pre-wetting resin with the right (top secret ) solution will activate protonation of nitrogen in functional groups allowing the adsorption of acid ( everybody remembering the hint about controlled decarboxilatio
of THCA to thc and living cbda in acidic form)
So if someone will start the new topic on zeolite and polymer resins Iāll will tell what would happen if someone stupid/curious will use zeolite/resins in packable distillation head.
Happy Hollidays !!!
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Once I clean them up, usually just redissolve for HPLC, if itās hard to tell Iāll use the LCMS. Right now Iām just mainly playing with pH right now, but I had some really cool results salting out fractions. I am also working my way through solvents. If itās safe to use, Iāve tried it. I like adding a little acid or base to methanol/ethanol. A good amount of phenolic analysis from wine crosses right over, but unfortunately for the longest the wine guys were artistic not scientific.
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dumb idea number 427: Biologists approach to THC isomerization
- over-express cannabinoid synthase of choice
- bind to agarose beads and setup for chromatography
- run crude over column and play with pH
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Lightly off topicā¦ And maybe @Photon_noir already solved the color problems with the opaline.
But doing a multiple size stack of zeolite (3a to 5a or something?) In a CRC, would it have some potential benefits in color remediation? A few people seemed to point out it would help, but Iām curious if anyoneās thinking about using this on thc-a heavy extracts to just help color.
(Yes I know I should just do it and report back 
)
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Rereading a tread i started some time back and trying to Remember the circumstances i think it works
Some detail in my
Hexane crude tread yet seems Reading @Termite his info
I should have atleast rinse the seives for higher yield
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Is this remediating THC or THCa?
Both for you half decarboxilate the oil prior to start !! Hmmm 
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Anything that can be made through an absorbent in the flask can be made through reflux first then ran through a wiper after.
You know I love d8, and I use to make it with absorbents in the flask. Itās not very scalable though.
Iād rather reflux in a reactor and then distill again after in a wiper.
Guaranteed to be quicker
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Update to #427:
Skip the beads: Just express that engineered synthase on the outside of some handy critter in as fashion such as this https://jb.asm.org/content/jb/177/6/1470.full.pdf. then use the critter instead of beadsā¦removes the need to purify the protein or attach it to beads.
media costs = feeding your bioreactor to grow more of whatever critter you chose.
edit: remember, the DE which is a primary component of many of your color remediation or filtration media was a critter at some point. just shortening the wait timeā¦by moving some bits around.
bonus points if you harvest the bacteria in a centrifuge, wash them in-situ, then perform your binding and pH washes without leaving the fuge.
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Iām firing this lil guy up shortly, itās hooked up to an LC that I havenāt even booted up yetā¦ one thing at a time
Send me samples to run we got our analytics dept running full steam ahead real shortly
Thanks to @anon6488101 da real MVP
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@Ruwan one more reason to get that big fancy bioreactor from your homies back in Wiscoā¦ I miss fermentation so much
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ELSD is not going to work well on CBD and THC. Linearity will be an issue.