Just a reminder for preparation on these reactions & steps to help with higher successful conversion rates. If anyone has any questions I’m always available. 
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I think this is definitely the case. For the intermediate of d8-CBD is never found.
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Interesting point since none of us have identified d8-CBD on a chromatograph. Has anyone attempted to make d8-CBD to test this? I think this could give us an opportunity to understand a possible intermediate and see how it behaves under analytics.
On a side note… doesn’t CBD obey different IUPAC rules so it wouldn’t technically be called d8-CBD? More like d6-CBD?
Probably a stupid question, why is iso always starting material and not a broad spec distillate?
Cause with a more pure input you won’t have as many side reactions or a low TAC overall. Broad spectrum will always create different peaks & unknowns as it will have “impurities”. Hope that helps clarify
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Start reading here:
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OMG. Yes let’s rat around hundreds of compounds in a Lewis Acid, heat and halides and see what we make.
I tested some like this. There are so many peaks and compounds that our 2.2 hour method is full of peaks back to back for over 1.5 hours.
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Lmao reminds me of a few coas I’ve seen that had 20+ peaks I couldn’t imagine making a product like that & putting it out.
Those testing methods don’t show all the peaks like I’m seeing on a mass spec. They only show a very limited period.
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I know methods are very touchy and take a lot to develop, but can you give me some insight on what that method looks like? Just start cold and ramp very slowly on a really long column? Obviously it’s a lot of run time to dial in but is it more or less finicky than method development for a 15 min method otherwise?
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What’s your opinion on ion exchange resins
As catalyst ? Several get a yields on D8
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Amberlyst catalysts are great as long as there is no water. We have a food grade flavor that is synthesized with Amerlyst in a column .We conduct the reaction in the vapor phase. Downside is if water touches our target product then the reaction reverses. Lastly, we found the reaction only occurs in the vapor phase.
So we pack the column with sieve + Amerblyst + sieve. We boil a solvent on the bottom, feed our raw material in the top. The water from the reaction is captured by the sieve. the product goes in the bottoms. The solvent boils off the top of the column, is condensed and is recycled. After a while we empty the bottom and distill the raw material out. We have no byproducts. This is a food grade flavor.
Perfect product, no byproducts. In other reactions with Amberlyst you will get byproducts unless you immediately remove the water. Run a mass spec and see for yourself.
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Man…
Can’t wait for you to start dropping more shit like this.
You up for a consult once this shit show is over? Would love to get some education on your past and present work 
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Can I be a fly on that wall if it happens please? @HeisenbergInd, and @iontrap?
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I’m reluctant to share anything. Take our nice, clean, food grade, no byproduct synthesis that is tested every batch extensively my mass spectrometer and hand it to a D8 manufacturer:
A leaky process
overheated column
Likely cracking the solvent do to localized high temps from Amazon junk
Feed raw material quicker - after all the faster I feed it the more i get!
Buy cheap reagents and test nothing
Just let solvent go out the top - it’s cheap and disperses well to poison the neighbors.
And for instant gratification flash distill the solvent off.
result: hundreds of byproducts and a toxic food flavor. The new D8.
Edit: This flavor sells for over $50/gram so it’s worth a lot more than D8. Always easier money to be made than D8 junk.
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Would you or anyone else have a resource off the top of your head to read more into testing the purity of the reagents?
You should have inhouse analytics. In GMP it’s manditory. Check with kca or sandstone.
Nah… not even wanting anything related to D8. I’ll figure that one out on my own. It’s been my pet project and wanna finish what I started. I’tll take me some time, but I’ll nail it. You’ve given us all more then enough for me to play with.
I’m talking about other cool shit. Whatever you think would be fun to play with. Just for my own thing.
I’m a day trader by trade so I don’t do this for money. I do it so I have an excuse to get outta the house and have some quiet time 
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FID analysis is sufficient?
I always pre-distill my solvents. ALWAYS. Stored with activated 3a and 4a beads.
But, I also start off with lab grade EVERYTHING.
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