RSO - ISO vs Ethanol

I agree but our understanding is still so rudementary that i would not dare give advise
I mean seiously he gives 600mg dose 3x aday without vacuum i estimate 4% residual solvent those numbers are well within msds

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600 mg 2x (1:1 ratio) a day and occasoinally a 200mg dose inbetween as needed.

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I have also be trying to figure out a carrier oil that we know will work that you can mix with the oil to provide more mg of thc/cbd in the blood and carried through the membrane walls and move toward more of a 30-40% absorption rather than a 4-20%.

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Question?

We focus on max mg of thc/cbd. But I never can find anywhere that discusses absorption and using carrier oils to maximize the amount of total THC/CBD in mg to the body. Does anyone have information on this or now where I can find that.

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Ever tought of carriers. Treu the skin
There are some terpines with this “power” and dmso of course

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Lecitine enhances absorbtion
And recral administration gives higher numbers according to some

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We talked about rectally and she was not a fan, but it is the best… I have read it helps get the thc to the blood without the high as long as you can keep it in the spincter. Anything that goes passed gets absorbed with the high.

I have read you can distill with acetate and convert it from thc9 to thc11, which increases the potency and in return gives you better results.

I will look into lecitine and see if I can find out how much it increases the bioavailability via ingestion through cell walls. Thanks.

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Rectal and liver dont discriminate against getting high. Either orifice will get you high. Rectally gets you higher, as the liver doesnt filter out most of the high.

Chemist on future won t make you much money buth might make a diffrance to some please help

How to make delta 9 to delta 11 ?

@richpel @anon93688 @qga @drjackhughes and all others that i might have missed

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The only input I can say other than keep doing what is working is that iso is a more abrasive solvent & that’s the reason you’re pulling more volatile fats lipids & waxes, the only issue is to be sure all of your moisture has left the extract & if needed I’ve looked into different oils & being a know nutrition fact of almond being high among many many other natural resources for defense against cancer cell growth, I just looked into the oil benefits itself & if you’d like give it a look Free Radicals, Antioxidants in Disease and Health - PMC it’s worth the read to evaluate some new options by only changing your carrier & adding extra benefits, happy infusing, I hope the little one is doing well! I know RSO & coconut oil has helped my mothers skin cancer extremely, she uses a qtip head size for application & within days she’s heading wide open oozing cancer abrasions. Can post pictures if needed or if you’d like to see dm me preferably. But if I were you, possibly try a blind study to see the different in your carrier? Not on compromised immune systems obviously but possibly someone who can honestly assure you of your results without a unfortunate event.

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pictured is my rso from iso & a jar of it diluted into coco oil, clarity is what I shoot for. Clean product & can send over a SOP for you to try out. The OG packs are a full spectrum iso disty I produced & learned about the tek of how to remove complete moisture from iso for perfect stabilization & no merky residues.

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Hope this helps!

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@Sparky75 are you taking about making 11-hydroxy THC?

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Actually the process is in the alchemy book I think wrote in 1974. I ordered it from amazon. Cannabis Alchemy: The Art of Modern Hashmaking author is gold. I read it. But I am not as experienced at all this as people on this board. However, I have took much time to understand the science and chemistry behind why it works and what works. At the end of the day, it does not matter much about what we make in the beginning, but the bioavailibility in the end and what medicine actually gets into our system. I would love for her to go rectal, but at her age, I get it. I just try to make her comfortable. It is working slower, but I think if I could get higher doses deliver, when I say delivered the actual amount delivered to the blood stream. That is why I think bioavailibility is so important. I am no expert in either, but I have have learned much on my journey and read many vivo and vitro studies trying to figure this out. We focus on oil and high thc/cbd and that is very important. I feel we are in the beginning stages of things until the government deschedules it, so we can have human trials. I think the next step is bioavailibility. If I can give 200 mg and deliver 100mg, thats cost effective compared to 500mg at 4% 20mg and more effective, even at 10% it is only 50mg. Anyway, maybe someone with more knowledge can elaborate.

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Send me an adres i will send whatever hou need (cost costefective :grin:)

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Actually her immune system is up now, which you can see by the numbers i posted. Thats a whole different topic. I have focused on terpenoid mixtures to add, like carophyllene, which assists thc to bind to cb2 receptors, and with her typ of aml it shows an abundance of cb2 receptors in vitro trials. So ii felt it necessary to add that as well to help with the absorption. But we we talk about synergism, we have to think about what is particular best for skin, tumor, and blood cancers. They all differ and from what I read I tried to put the best mix possible together to assist the thc and cbd to do their job. I actually add turmeric oil pure, it is supposed to activate cb1 receptors and I would love to find the case study that shows at 1mg a day it helped a cancer patient and we know the eastern world has less cancer rates, but that is all they eat every meal. Anyway, so much unknown science. I hope we can figure this all out one day.

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No, I am not. I am not that advanced in distillation, but think I may know how, but what I am doing seems to be working, so I am almost afraid to change. If I make changes they are small and slow and I wait on results before changing. We had 5 point increases and I made an adjustment and waited and now we are at 7 points. So I am very cautious when making changes.

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O one mire that helps the absorption is oxigen several patients that i have helped
Their docter recomendef thc/cbd oils
Wich are illegal here by law
Once the patient got a hold of them the doc would prescribe oxigen therapie
To engance the cannabinoid uptake
Even thou prescribed for a diffrent reason for the law and insurance company

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So we have high thc and cbd, is coco oil going to provide a better carrier oil to supply bioavailibility into the blood stream than just direct concentrate. That is the big question. We can dilute it to say 100mg per ml versus say 500ml. if we can get 50% bioavailibility into the bloodstream you get 50mg. However at 500mg at 10% we get the same thing. The question is how much bioavailibility does coco oil provide and how many total mg are in X amount of product. Clear is pretty and that is what sells, but I look at it medically and do not know the answer, but I am dealing with life and death, not an average disease or recreational situation. Everyone wants the golden oil, i get that. I wish will had enough data to figure all this out. Again, government needs to deschedule so we can test bioavailibility in humans.

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See, I dont understand the difference between ethonal and ISO, other than ISO pulls more Cholorophyll, which enhances oxygen, not to mention the lipids(fat), which provide an natural carrier. Is it a small difference or big difference between soilvents. Oxygen and carrier oil being provided at a strong level by ISO or is it such a small amount it does not matter.

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