We’re a manufacturer struggling with repeated PBZ contamination issues and looking for some insights. This issue has lasted a few months now so I’m going to try to hit just the bullet points, but please let me know what questions you have!
Process:
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Optional Terpene extraction with CO2 extractor. > Store Terpenes
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Butane Extraction
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Dissolve in EtOH
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Cryofreeze.
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Filter using Buchner Funnel & Filter Flasks.
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Recover EtOH via 20L AI RotoVap.
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Decarb in 2L AI SPD.
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Pass through SPD once or twice.
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Test with a 3rd Party Lab.
We process with both CO2 and hydrocarbon extraction, occasionally using both for the same material batch.
Background:
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Received biomass from a local cultivator, tested and approved.
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After processing half the material, we had distillate fail for PBZ at 0.8 ppm (Typical LOQ is about 0.009 ppm)
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R&D tests on related materials showed no contamination. Tested CO2 terpenes extracted previously, although not all batches were identical to failed material, BHO crude (processed after failing lot), and unprocessed biomass.
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Another batch of distillate tested even higher for PBZ at 1 ppm.
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Post-failure, equipment and solvents were cleaned. New tests still showed failures.
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On-site lab sampling showed very small traces of PBZ on all equipment, but no significant source. Additionally, exterior soil samples were taken and PBZ not detected.
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Following advice from a PBZ manufacturer, all rubber/plastic that came in contact with oil was replaced.
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Success was achieved with 8 consecutive lots of distillate passing after replacing all plastics and only running CO2 extractor.
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Needed throughput of hydrocarbon extractor so did a small test run and tested crude, prior to post processing. Crude came back ND, was released into post production line.
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Distillate which came from hydrocarbon extraction saw further failures with levels just slightly above the LOQ.
Key Points:
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Even after multiple solvent dumps and equipment cleanings, the issue persists.
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BHO crude tests clean but post-distillation, we’re observing failures.
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Replacements of all rubber/plastic parts saw an initial improvement, but the issue returned.
Given our limitations in replacing the entire equipment setup, we’re looking for advice. Specifically, why does BHO crude test clean, but later stages fails? Any guidance on resolving this PBZ contamination issue would be immensely appreciated. Thank you so much for your time!
