So I have been using the Cannasol Technologies All-in-one surfactant. It is expensiver than frig, but it does create stable nanoemulsions. I will call them up and see what they suggest for this project so that I can hit the ground running.
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Ok. Prostate cancer is a hormone driver cancer and some take medicines to lower their testosterone so the cancer doesnāt spread, do you think with Icariin being an aphrodisiac that it would be counterintuitive for prostate cancer?
Icariside II shows promise: The Impact of Icariside II on Human Prostate Cancer Cell Proliferation, Mobility, and Autophagy via PI3K-AKT-mTOR Signaling Pathway - PubMed
Thereās more studies just a google search away. Icariside II is a one of the main metabolites of Icariin (Source), so icariin should share these effects (I think?).
Icariin is known to increase testosterone though so Iām not sure how hormones would come into play.
Please return the 2 t10 shafts you stole from your customer. It has been several months, much longer than the 3 business days you purport.
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I hope this becomes/is a viable solution to treating cancer. Along with many other potential options.
Thanks for bringing this to light, itās interesting!
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When I plug that doi into Sci Hub I get the full 25 page report?
Have you set your sights on one particular anti cancer flavonoid?
And the plane source, or were you just thinking on doubling up
Extracting the āhemp biomassā?
Do you happen to know exactly what type of cancer he has??
Best regards,
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Dear friend,
The idea of extracting flavonoids comes
From the option that I now have (thx to you 
) where I have plenty of crude thatās been treated with little heat and that I am passing over resin beads that attract flavonoids
It s harder than expected to find a lab that can identifie them so I am basically yust collecting in the blind still
But the notion that they are there to pick up yust is to tempting to let them go 
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Wrong format
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Double wrong format
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Hi, this is a great plant botanical chemistry project, so I donāt want to distract from that.
But if the primary goal is treating your uncle Iād suggest that bioavailability is probably no actually limiting factor.
Rather, that would be easily solved by just using a higher dose of an existing preparation to reach the desired dose of the target compound. As we know from cannabis sometimes there are other therapeutically active plant compounds which enhance absorption or synergise with the primary compound, so āpurerā or āmore availableā isnāt always better.
Regardless while this botanical could be a useful treatment I bet there are 10+ promising botanical and another 10+ promising pharmaceutical treatments for prostate cancer with better evidence and a faster path to treatment.
Iām a veterinarian and have recently watched a couple of products I was involved with or watched early stage trials of 10 years ago come to market including the anti cancer drug extracted from a rainforest plant which is now available for pets and humans. That was all well after theyād formulated. Thatās just demonstrating efficacy and getting registration. And realistically, if itās not effective, why bother? Lots of things look good in vitro or in mice but there is a long way between animal trials and a usable, safe and actually effective human therapeutic.
A lot of prostate cancers have low aggressiveness and relatively long survival times are pretty common (compared to nasty cancers like Pancreatic, ovarian, brain etc) but nonetheless the efficacy of established treatments is pretty good and can extend this.
In particular any reproductive cancer is usually responsive to hormonal treatment. Thatās on top of all the normal range of treatments and pretty good surgical outcomes.
Of course we shouldnāt forget one of the most famous botanical treatments for Prostate disease and cancer: Saw Palmetto.
This took many years to go mainstream but is now widely used to manage prostate disease. And itās one of those funny situations that even after isolation and lots of clinical trials the data is still mixed as to whether it works or not. And thatās a proven āwinnerā of the promising plant compound commercialisation game.
https://www.mountsinai.org/health-library/herb/saw-palmetto#:~:text=When%20the%20prostate%20gland%20is,size%20of%20the%20prostate%20gland.
And of course this being a cannabis site you shouldnāt go past cannabinoids especially acid cannabinoids and THC, but if your uncle was anti-cannabis/drugs then just the acid forms (but especially THCA) are very promising from an anticancer effect.
So in summary Iād suggest exploring the fast and easy options first as this condition is sometimes pretty treatable - but by all means I donāt mean to distract from the hijack the Icariin project concept or discussion.
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Any updates to this thread?! Was this man ever able to help his uncle and was a more bioavailable form attained? Subbed for sure Iām really praying for something awesome from this! What a break through it would be. I have plenty of people I know this could help.
Hey man!
@MedicineManHempCo made a nanoemulsion for me, it was made with ingredients tuned for CBD though, and the end product wasnāt perfect (there was some separations, low clarity) but it was still much more bioavailable than raw Icariin.
As far as how it went with my uncle, I canāt really say anything for sure. Heās still in chemotherapy and has had some improvement, but that could be solely due to the chemo and not the Icariin. I donāt think heās taking the Icariin because once it came down to it there was alot of hesitation with the doctors telling him to stay off ALL supplements (they didnāt even give it consideration 
). Also, he wanted to know if the chemo would work alone, which so far it has! If there happens to be a road block in progress heāll likely try the Icariin to help break through it. Hopefully he doesnāt have to. Weāre all very grateful for the progress heās made and are hoping for lots more 
Regardless, I have alot of faith in Icariin to improve many peoples lives with or without cancer, so Iāve been actively working on getting a more stable nanoemulsion developed. Weāve just recently gotten a stable, clear nanoemulsion with 50nm particle size created and are going to do some testing on it. First on itās effects on hormone levels, mood, depression / motivation, and hopefully later on itās anti cancer effects. Once we have more available, Iām happy to send it to any interested people at-cost.
Thanks for checking in 
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Glad to hear your uncle is doing the best he can given his circumstances. I do hate that the emulsion we made separated. I am also glad you found someone to help you with it as I just larp as a Chemistā¢ļø and know very little about emulsions. I hope your uncle continues kicking cancers ass, brotha!
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Any updates TraphouseFish?