How preserving is CPC when separating cannabinoids?

Newbie here.
If I am violating any forum rule, please feel free to correct me.
I made some search in this forum, unsuccessfully, but I may have missed some important threads. If I posted in the wrong sub-forum, please help me move it to the right one.

If wanted to obtain from a distillate (or crude) both CBD isolate on one side AND a “CBD-poor” (THC-rich) large spectrum extract, would CPC or other chromatographic technique be appropriate? How much of cannabinoids are lost in the process?

What do labs that use CPC with the rest of the extract, once they have separated the CBD fraction?

Many thanks in reading this post and I warmly welcome any educative message.