Homogenized micro-emulsion vs. sonicator toll processor for nano-emulsion

Hempire Building
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Hey! I was wondering what your recipe is for a stable thc syup using a homogenizer, if you dont mind. Im just about to place an order for the cat x1000d homgenizer do you think thats a good choice?
Thanks!

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They make solid probes without replaceable tips

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Titanium is a heavy metal :metal:

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Is it not the case that a .2 um membrane filter can safely remove the metal shavings from the solution after sonication is complete?

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I jist bm posted about this in another thread

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Is the recommendation for 3-5 parts gum 3-5 parts dry gum or 3-5 parts hydrated gum (so the weight of water+gum)?

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that emulsion you’re describing is going to break the second you apply appropriate heat if you’re making gummies… and wont stay in a beverage for v long if you’re going that route. mssg me!

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aren’t the horns proven to degrade?

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Yes, metal flakes will come off the horn. Any liquid product like this emulsion should be put through a 0.22u sterile filtration prior to downstream use or direct consumption, this would remove those metal particles. We’re not talking about dissolved heavy metal contamination, but literal microscopic flakes of the sonication horn that fall into solution during sonication.

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Yes they are.
There are arguments on whether the Titanium Oxide is nano, micro, or macro particulate. Most literature supports Zoraku’s recommendation.

I would not be surprised over nanoparticulate Titanium/Titanium Dioxide. In practice, I’ve found its mostly larger particles(~.5um) that can be filtered out. You can usually spot these pieces with naked eye. They look like tiny black rocks at the bottom of your solution. In sensitive food and drug applications that require ultrasonics, they use indirect sonication to avoid contamination. In addition to the tip of the ultrasonic horn shedding metal, cavitation can cause pitting in metal tanks. Even very highly polished 316L will start to pit and shed steel particulate which is WAY WORSE than titanium particulate from the horn.
Carefully calculating vessel geometry, appropriate materials, and ultrasonic fields can help mitigate tank pitting issues(i.e. flowcells, US reactors, etc).

https://www.sciencedirect.com/science/article/abs/pii/S0032591022000511
https://setac.onlinelibrary.wiley.com/doi/10.1002/etc.2123

https://onlinelibrary.wiley.com/doi/full/10.1002/osi2.1001(Dangers of nanoparticulate of Titanium Dioxide)

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