Homogenized micro-emulsion vs. sonicator toll processor for nano-emulsion


The sonicator tip my man- there’s a reason they are replaceable- they corrode.
trust me on this - and google around it is not hard to find papers and studies that prove these claims.


I have ways to make micelles with very cheaply sourced equipment but I ain’t tellin’ just anybody :wink:


Fair enough, you’re definitely correct.

I wonder how well enclosed-sonication devices avoid this issue…for instance, things like ultra sonic washers.

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You need to use a piece called a cup horn- https://www.sonicator.com/pages/direct-indirect-sonication-methods

A flowcell cup horn would enable inline continuous processing


Are you referring to the condensation method of forming emulsions?


Nope- I’m talking about Michelle formation.



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  • Josh

I wouldn’t say high pressure homogenization is unscalable. They use to make homogenized milk!


No of course not , just wanted to mention how our method is , as scale-able if not more so than most techs while being consistent , stable , cheap and effective.


@Rowan you can filter the metal (in most cases titanium) nano particles out of solution when sterile filtering, which you should be doing anyways. The particles that come off the sonotrode are 600-800 nm if my memory is right, and a sterile filter is 220 nm.