I have over 100% COA, what would that even prove anyway?
Reality is you cannot definitely say HHC or any converted cannabinoid is 100% safe or unsafe.
Making basely assumptions @TurahTurah is not science either, fyi.
The only true fact is 100,000s of consumers have ingested, inhaled, boofed HHC (from many vendors). They are all fine for the short term, it is up to them what they want to consume.
Safety is important, since you’re sitting on pure HHC entiomers are you about to drop that 99.9% HHC SOP tek for the forum to benefit from?
All HHC that is made from d8/d9 will be diastereomeric mixtures. Only one of the diastereomers is active.
All HHC made from olivetol and racemic citronellal will result in a racemic mixture of HHC; (6aR,9R,10aR) and (6aS,9S,10aS). These two molecules, mirror images of each other, will show up as one peak on LC unless the stationary phase is chiral. Of these two molecules, biological activity in all likelihood only reside in the all-R enantiomer.
In order to arrive at non-racemic, non-diastereomeric HHC, the only currently available strategy involves using enantiomerically pure R (or S) -citronellal, and for the analysis to separate the two, you would have to use chiral chromatography.
To get to 9R-HHC only from d8/d9 by reducing the double bond involves a lot of chromatographic separation of the diastereomers.
In the case of d8/d9-THC there’s only one double bond to be hydrogenated so in this case, I fail to see how any partially hydrogenated products are even theoretically possible.
Seriously? It’s entropy lots of byproducts are possible. You’re adding energy to a system and encouraging chaos
Catalytic hydrogenation is one of the cleanest reactions known to mankind. The hydrogen molecule H2 gets cleanly added to either side of the double bond
(that’s why there are two products formed). This reaction takes place at ambient temperature and 1 atmosphere of hydrogen. Exceedingly clean unless you use unnecessarily harsh conditions (elevated temperature, high pressure hydrogen).
The way you’ve explained the h2 attaching to the double bond makes me think it would be pretty hard to get some kid of intermediate
I have heard of people making cbn during hydrogenation which is pretty unusual, idk what else you could really make
Actually, the reduction of a double bond is entropically disfavored; two molecules (one H2 and one d8/d9) come together and form one molecule of HHC. That’s the prototypical notion of a decrease in entropy; less “chaos” after than before.
Catalytic hydrogenation is in principle reversible as in catalytic dehydrogenation. Dehydrogenation requires more energy input to occur and I expect people seeing CBN as a side product are using too harsh conditions.
They are ill-informed (de)hydrogenators.
Lol this poor sales thread
Really good info here
He’s getting free bumps all day - it’s not all bad.
Yeah I don’t disagree. The information here is really good, it’s just hard to remember there’s a product for sale somewhere upstream.
If it’s good for @eyeworm I’m all for it. I didn’t want his thread to potentially be derailed
@eyeworm, if you want all the chatter cut out just tag a level 4 and they’ll move the BS
Better Science
Easy tiger @TurahTurah is well versed in hydrogenation and has some good advice
Treu that testing is hard but I would recomend contacting your nearest university and see if they have capability s
When it comes to safety, you can sometimes get away with racemates, and while I do think its ok with HHC, pharma companies are held to this standards. If you are a phamacuical company, you MUST resolve enantiomers and diastereomers before your drug is ready for use.
I realize we are not pharma, but usually they are held to such a low standard (compared to what they should be held to) that we should accept those guidelines.
I do trust your skill and expertise enough to clean up palladium (though please do get it tested because shit happens), but do resolve the pair.
Yes, Nabilone (a cannabinoid derivative) is sold as the racemate, at least it was last time I checked.
Usually, the word resolve in organic chemistry implies that an enantiomeric pair is separated.
In the case of HHC from d8 or d9-THC, the products are diastereomeric mixtures and they are separated, not resolved.
And I’m still curious what exactly @TurahTurah meant when she mentioned “non-racemic” HHC. I think she meant to say diastereomerically pure HHC (from d8/d9). Confirmation would be great!
Thanks!
You and me both want a pure 9R cart 
You are correct with resolve vs separate (I think), meant more in the spirit of chiral centers
What’s special about these chiral cellulose or amylase columns? Is the surface functionalized in some way or is it a property of cellulose that makes it able to separate chiral molecules?
Also is there such thing as acetyl hhc?