The less super saturation, the larger the crystal. Add more solvent. Don’t cool so fast if you’re worried. Take your time. Big crystals take a lil longer unless you’ve really honed your process.
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I just wanted to add: if we look at the mixture you’re attempting crystallize, we have to consider that all the components have different solubilities in your solvent, solubilities which are all dependent on heat in different ways.
It might simply be a matter of: too many different components crowding up the mixture and therefore several different crystal structures forming alongside each other?
@Photon_noir is the resident chemistry whiz as far as I can tell, maybe this question interests you?
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You have a rough plot, Man! How can I possibly improve upon that? Certainly with all the inherent variables, I cannot. You are correct. Nothing to add, here! 
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What’s up man, I’m hoping to get some tips on crystallizing CBD using some eTOH extracted crude and pentane.
I understand the basic concept of it all but have some questions still. I am without a chromatagraph but understand it can still be done. I’d love to talk to someone who understands the process.
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I’m in the process of designing a semi-large scale setup for making CBD isolate. I’m currently working with hemp materials (as the flower material is still not legalized in the state I’ll be working in). I’m really working around the 0.3% THC factor when considering my design, as the product would be marketed under CBD licenses.
I’ve proposed several solvents to consider when performing the extraction, but I am personally not well versed in knowing which will yield the best results for short path systems. For instance, I’ve recently read good things about EtOH in short path, but I know the extract can be a headache to deal with considering all the BS you pull.
Would you be able to details some of your industrial setup and/or comment the use of several solvents. I’m mainly considering designs with pentanes, aromatics, and simple alcohols. What are some obstacles I should consider when designing?
@TheDarkStallion Cold EtOH doesn’t seem to have that issue with pulling all the BS. Our current CBD supplier sold all their CO2 equipment recently in favor of ethanol just because they’ve been able to process so much more material. Looks like the key to clean crude is keeping it cold, though.
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Tried sending you a PM about your isolate process but I’m not allowed to. Do I need to be on here more than 5min to do so?
I’m trying to run some preliminary lab experiments to isolate CBD in a large column. What solvents are generally used to do this? I have plenty of hexanes, DCM, and AcO, but I can’t find any good papers on which solvents work best and if I have to process the eluent any further after the first run.
Also, is there a better system to learn about rather than forward phase column chromatography? I’m lab trained, but I don’t have any experience with fancy reverse phase, and orthogonal flash chromatography. Thanks all!
IT doesn t 
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The link doesn t work 
lololo sorry I will trouble shoot this
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Try this
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Great paper. Thank you!
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Are you collecting the mother liquor of this industrial scale activity for later workup to isolate minors ? Just curious.
For large scale CBD processing I always recommend Heptane extraction to my clients. It’s the most efficient and easiest to purify. I’m setting up a 25t/day facility for someone right now and this is the path I have in mind for them.
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How much you charge for consultation?
Winterizing hot or cold
LLE in the pre distillation sop
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What are the benefits of using heptane vs alcohol? Cost?