Difference between Hemp Derived Delta 9 vs Marijuana Derived Delta 9

Can anyone explain the difference between Hemp Derived Delta 9 THC and Cannabis Derived Delta 9? Is the High different from a Marijuana Delta 9 Pen than a Hemp Delta 9 pen?

From what I’ve read its the exact same chemical structure just extracted from different things. I am hearing smokers say 1 of 2 things: that the high is nothing like that of a Real Cannabis Delta 9 pen or that the high is similar enough not to tell a difference.

What does everyone think? Thank you for the insight as always my friends.

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Great discussion. My surmise is that it’s more about what else is in there. There’s no such thing as 100% distillate. @Photon_noir @PharmExOregon

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Ive made distillate that tested at 1000mg/g by MS which was tested by KCA so I wouldn’t say thats theres no such thing as 100% distillate

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80 posts were split to a new topic: Hemp d9/acetate off topic

As far as the difference between hemp derived and cannabis derived… Let’s start with making clear that we are talking about actual hemp NOT what people try to skirt the law by calling D9 THCA hemp derived.

There can be and there are differences between synthetically altered CBD into Delta 9 and naturally occurring Delta 9. Delta 9 THC can exist in different states , S - R, CIS - TRANS, EXO - ENDO. Have this as your starting point in trying to understand the differences and go from there bro.

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Argg you expect to much from fellow members to understand the last interesting holy grail :stuck_out_tongue_winking_eye:

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He asked and I answered… Albeit just the tip of the iceberg.

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right and again how do you expect to understand this without being able to test for all that shit in house? just send to kca? can they even test for stero specific isomwers of d9 thc?

Well… Going back to the starting point of this whole conversation… You should be able to tell the difference in the way it feels.

Gotta start somewhere…

Could go back and start with: “hemp” & “marijuana” are both cannabis…

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so you think the same identical compimd feels differnt between being natural or synthetic? that stero chemistry has nothing to do with it?

i agree with the terps defiently added different effect on the same material but how do we know the distillate is all the same compound in the end? d amp and L amphetamine gives different results depending on the ratios of isomers how we knoes this aint the samer>?

Dude I say the exact opposite I say that stereochemistry has absolutely everything to do with it and when you synthesize you affect the stereochemistry

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thats what im saying sorry and how we not knoes the sterochemisty in isomezied d9 , synthezized d9 and natural extracted d9 and are all the same>? can =a lab like KCAs test that specific?

I think it was about a year ago I was talking to one of the nicest guys and brightest minds on this forum and he was telling me that he found out that when synthesizing hhc there was a significant difference in and one of the above mentioned variants of THC. And the way he explained it it is a very significant difference. (Out of respect to him and his hard work in testing and figuring out this specific variant I will not disclose it)

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for sure i can get behind that - and the addition of added terps probablyy also effects all of thosw differently as well maybe

Terps are also just like almost everything else in this universe is greatly affected by stereochemistry

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i mean its true4s in other drugz that have stero specific iomers so should carry over and aplly here no?

Unless I’m mistaken I think that absolutely every drug known to men is to varying degrees affected by different stereochemistry… The majority of drugs are extremely affected.

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Those telling you they are “identical” are likely sourcing so called “thca flower” which IS identical to “marijuana” except maybe for the paperwork.

Those who say they are different, could be getting any number of different things.

Almost always a mix of D8 & D9, and without a doubt containing other isomers as well.

No, the stereochemistry between enzymatically and chemically synthesized compounds is rarely identical.

Yes, that difference is likely to change the way the molecule(s) interact with your receptors.

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Take for example Ritalin (methylphenidate)

D-threo-methylphenidate (also known as dexmethylphenidate) - This is the active form of methylphenidate that is primarily responsible for its pharmacological effects as a stimulant.

L-threo-methylphenidate - This enantiomer has different pharmacological properties compared to its D-threo counterpart. L-threo-methylphenidate has been found to have sedative effects rather than stimulant effects.

Therefore, L-threo-methylphenidate is the stereoisomer of Ritalin that exhibits sedative properties.

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