Never done for conversions but I have done a lot of ion chromatography for purification of virus. Used GE fineline columns for it. (Edit: anion exchange specifically)
How much larger are you trying to go? we need and idea on scale. Without reinventing the wheel you can easily do reactions in a 100L glass reactor. after you scale past that you can add another reactor.
there are benefits to running multiple reactors vs one. if something goes wrong in a 100l reactor you could lose that batch, or a good amount of it. if something goes wrong in a 500l batch well you lose 5x the product.
Ive seen large glass lined reactors used for sale that are thousands of gallons, two stories tall and all. Im sure someone probably makes 200L glass reactors, but over that size Ive only seen glass lined stainless reactors
We run 2) 100L glass reactors. We run the rxn in one then move the solution to the other for washing. The one we wash in has a filter on the bottom for efficiency.
If you’re stuck in the mindset of batch chemistry you can get a used glass lined steel reactor as big as 1000 gallons. Otherwise, flow chemistry is the future of fine chemical manufacturing in general. Just depends what you’re capable of biting off.