Tbh I recommend looking into hiring a consultant if you need much help selecting catalysts and solvents. Many of us on here, myself included, sell the parameters of our reactions and would happily walk you through your reactions. DM me if you want.
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Di ethyl ether dry conditions will give 98%D8
With ptsa on a small scale very usefull
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It‘s a great idea! Maybe its better to purge!
Diethylether have boiling point of 34,6*C
I know someone who made a izo with petrolether (bp. ~40-45* C)
He made the following recipe:
1g Cbd + 100mg ptsa + 50ml petrolether in boiling flask, heat up and reflux 2h, wash 3x times with water and bicarbonate and evaporate solvent off.
Advantage: you make d8, do you don‘t dry ptsa completely and you don‘t need intern atmosphere (N2 or Argon), so the izo is easy made.
Tip: destill solvent with vacuum, so you can safe your product of oxidation!
He wasn‘t able to test his result, but it was good & taste like nothing!
He describe one thing: he got a clear, waxy light yellow oil, which is really hard by roomtemperature, when he left it for some days on air the product get a deep red colour. Is it normal to get oxidation after izo?
I know that d9 gets oxidation but d8, too?
@Roguelab what do you think of the Parameter? More acid / longer/shorter reflux?
Because when he wash with bicarbonate there was NO fizzle, so all acid was use for izo?
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D8 oxidizes readily
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Did anyone know a solvent which is able to extract cannabinoids out of toluene/xylene?
For example you make a izo which a solution of acid + cbd + xylene, wash and neutralize, separate xylene out of water and then extract the thc out of xylene which this solvent.
For example you can do a acid/base extraction, but is that able with cannabinoids?
Methanol
But also, water washes can remove any catalysts were using I’m pretty sure
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Methanol is miscible with Toluene and Xylene, so that’s not going to work.
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Oops I stand corrected
ibarely ever use ptsa monohydrate in more than 1.5% by weight to cbd
so your 10 % schould be more than enough
even thou i am not sure you have stirrring gooing at that volume where loading more acid makes sense if there is no stirring
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Yes stirring is activ, Temperature goes to 45*C by reflux based on the solvent petrolether.
So you thought less acid is better?
And you recommend as solvent diethylether.
So do you think is 1g CBD + 15mg ptsa (1,5%) + diethylether a nice next run?
And what do you think is better 1 or 2 hours?
Best wishes!
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Run tests, report back
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Heptane is good for all sorts of lle purposing 
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Ptsa will dissolve a bit so the the reaction runs fast
Go easy when adding your acid drop by drop
Reflux time is around 2 hours on your scale
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Hi guys, do you reckon the isomerization process would work without having an isolate of CBD? Like drenching the CBD buds in acid and applying heat and time?
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The cleaner the input, the cleaner the output. What you describe would have worse results than likely any isomerization process that has been mentioned on the forum.
Isolate > distillate > crude > raw flower. The more compounds present at the time isomerization is being performed, the greater liklihood for side reactions and undesirable results. People are using isolate for this reason, primarily.
Edit: After rereading, that sounded super harsh, and I apologize if it was taken as such. There’s no such thing as stupid questions, only stupid answers. Please don’t let my morning terseness discourage you from continuing to ask questions!
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Thanks for tuning in. Fair enough. But I don’t have nor the equipment nor the money to buy CBD isolate. In Europe this is very expensive. However I have the flowers and was trying my luck. I guess I could do an oil extraction of cannabinoids first before going to isomerization them. Any other ideas?
Find a cheap importer on here for isolate
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@Roguelab may be able to help you source isolate in Europe that doesn’t cost an arm and a leg.
Crude will work better than raw flower, but it will still present you with a ton of side reactions and leave you with a large quantity of unknowns in your final product. I know what you want to do and why you want to do it, but I, personally, don’t have a good solution to your problem.
I know that there are a few threads that have some gems concerning the use of drysift or bubble hash and a rosin press to make isolate. While it would be time consuming and the yields would be terrible, it is possible to make (mostly clean) isolate like this. That could get you close enough to the starting point for avoiding unwanted reactions during the isomerization process.
Hopefully Rogue has a few ideas or tricks up his sleeve to help. Hate seeing people unable to access medicine.
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Ok, never thought that I can do that, great idea, is there a specific way to ask or look for this specifically? If so where? I don’t think I have the rights to post anything (being a fresh member). Thank you!
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Use the search icon to find isolate sale threads & you can refine your search by clicking more at the bottom left hand corner of the window that opens as you search then click the drop down window on the upper left hand & refine to latest posts to see who’s been most active & can help with sourcing good isolate.
Always remember to go over reviews in threads too!
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