2017-1: Delta-9-Tetrahydrocannabinol (Δ9-THC) Induce Neurogenesis and Improve Cognitive Performances of Male Sprague Dawley Rats

2017-1: Delta-9-Tetrahydrocannabinol (Δ9-THC) Induce Neurogenesisand Improve Cognitive Performances of Male Sprague Dawley Rats

“Administration of Δ9-THC was observed to enhance the neurogenesis in the
brain, especially in hippocampus thus improved the cognitive
function of rats.”

Smoking weed grows your brain. As do magic mushrooms!


This plant of ours has a plethora of benefits we dont even know about yet. Loving the site so far✌


Very interesting paper. It is important to note the U-shaped curve that indicates there is probably an optimal dose for this effect. It is hard to scale doses between rats and humans because rats have a much higher metabolism than humans.

In this study, the optimal dose is about 110mg for a 150lb human. But, you might want to drop that ten-fold to make up for the difference in human/rat metabolism. That translates to 11mg. That’s one California legal edible dose per day!

An important question is: does this effect hold up when the rats are in an enriched environment? The argument can be made that lab rats living in a simple cage on a regular feed schedule are deprived of enrichment, and may not be a valid baseline for a “healthy” model animal. Sometimes when the rats are put in a larger cage with lots of toys and objects to interact with, these effects on neurogenesis or altered stress responses will disappear. It’s a lot to think about.

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Maybe this will finally get the KissInjures, SoreOh’s, HerBurt Walkers of the world to stop kidnapping RH- coloboma children and extracting the resultant high levels of NGF and other neurogensis factors from them, as if they were food products. (Maddie McCann RIP)

Entheogens and empathogens, as tools to stay cognitively sharp ! Make sure your terps have plenty of alpha pinene gents !

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Weird how that would line up with what most states consider a single ‘dose’.