I’ve seen thc-o acetate being marketed as thc-x recently
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I opened this thread in disbelief thinking “has someone begun attempting to produce the orcinol series?”
But of course, no.
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Is it possible to acetylate only one of the Hydroxl groups. Maybe it’s only a theoretical metabolite.
Yes, at least on the back of my envelope.
Assuming equal reactivity and using one equivalent of acetylating reagent one should expect 1/3 diacetylation, 1/3 monoacetylation, and 1/3 unreacted CBG.
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Once a single phenol is acetylated the ring is partially deactivated, and so, would you still be
At that point?
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Mostly from an Electrophilic Aromatic Substitution point of view, I would think. But the nucleophilicity of an hydroxyl in a meta position shouldn’t decrease that much, I think.
Maybe the effect could be bigger if diacetylation of a 1,4-dihydroxybenzene was attempted?
I think the product distribution would be much closer to the statistical distribution I threw out rather than the ideal 100% monoacetylation.
I’ll try to look into acetylation of model compounds to see what I can find.
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Well folks, a few years have passed.
Is Cannabigerorcin (CBGo) worth experimenting/acquiring?
For what? Dont vape it.