THC-O-Phosphate was originally synthesized to create a way to inject D8 in the 70’s. It has a slower onset. Esters of cannabinoids will change everything we thought we knew in a few years.
3 Likes
THC-O-Phosphate probably acts like a pro-drug, needing the additional chemical group to be cleaved. Probably enzymatically.
I agree that medically speaking, water soluble, injectable cannabinoids would be wonderful, especially for delivery into and around tumors and such. Instant action from an injection is a bonus when seconds count in medicine.
Recreationally speaking, I wouldn’t advise one to shoot their weeds, but ain’t gonna hate on those that do. I’d some some bumps of some kinda thc salt type powder, ya know, fer science…
1 Like
That’s the idea. The specific ester used can control onset time, duration, etc. You could have something that acts as a fairly stable dose of CBD over 24 hours, 5 days, 2 weeks, 4 weeks etc. For most people this is unnecessary if they can easily consume it throughout their day but many severely ill patients are unable to keep up with this. I saw a similar patent on a sustained release CBC prodrug pop up recently.
@BigM I’m not sure if THC would still have an increased localized effect with an ester attached in this way. I really don’t know though as I’ve never considered this idea since it’s already way above my head at this point. Definitely an interesting concept that we will see rolled out in coming years when pharma gobbles up the whole industry. Unfortunately these same chemical modifications will be used to create some very dangerous synthetic cannabinoids too that will be exponentially stronger than cannabis ever intended.
4 Likes