They use pressure in that video. It’s actually what lead me to ask.
I remember the great one @Beaker uses a paintbrush air compressor or something along those lines
nitrogen is a safer solution…and may or may not be what the “flash pressure apparatus” referred to in the video actually consists of.
solvent choice and volume in play are both relevant when making risk/benefit calculations.
…but all three at the same space/time coordinates can seriously harsh your buzz.
seriously kids: DavidB GoFundMe for funeral costs and scholarship
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Why do you say to use Silica gel, then Alumicel N, then Alumicel A after magsil/alumicel B?
I never had very good results with normal silica but i didn’tadjust the ph of my solution before running it through which I’ve read affects it’s effectiveness a lot. But if i adjust the ph inline then it should work better. I prefer using magsil but not anywhere near 10:1 magsil:extract, that’s way overkill in my experience
And I’m trying to avoid using clays so that my flow rate isn’t slowed down a lot, at least until i start pushing everything with nitrogen
@TheFire210 , the concept in my instructions is in-line neutralization of pH. The Magsil and Alumicel B are both alkaline (high pH), so if they are at the top (entrance) of a CRC column, then using layers of more and more acidic (lower pH) media below them should help the solution to exit at a pH closer to neutral. Does that make sense?
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Yea the concept makes sense, what i was wondering is why you’re using silica AND magsil when magsil works 100x better than silica. Also why use so many types of alumicel, why not use magsil on top and alumicel A on bottom since it’s the lowest ph? Is there a specific purpose to stepping the ph down with multiple types of powders?
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Ah, well not particularly. That was just an example for remediation of the difficult pesticide: Spinosad. The more adsorbent functionality one uses, the better his chance of remediation success with such a pernicious pesty.
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You are suggesting ion exchange in aprotic solvent?
You are scavenging mobile H+ ions off a Lagmuir isotherm
to protonate phenolates in aprotic solvent…or are you suggesting the “CRC”
has bound water with low pH and you are actually doing a LLE?
Perhaps a little diagram would help? Or are we just talking about pH of water dissolved in alkane?
It is really amazing how people are thinking about pH…these days.
the original op said “dist” so we should assume decarbed?
not to be confused with the popular use of CRC on alkane-crude prior to diamond prep?
Where do those H+ ions come from? that is rhetorical of course…I am amused.
yes a diagram…perhaps?
Unless we try REALLY hard to ensure a system is anhydrous, there is ALWAYS some water present, @moronnabis . The one thing I feel you need to consistently remind yourself is that MOST chemistry is NON-ideal! 
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Unless there’s residual water in my heptane or magsil there’s definitely no water in the system… yes it’s definitely decarbed all the way since I’m remediating after 1st pass and then doing a 2nd pass for finished product.
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But does the water take on/dissolve any h+ ions from the column? If we wanted some kind of “neutral” system aren’t we vying for an exact amount of both high and low pH medias to perfectly neutralize?
Are we worried about isomerization or something? That won’t likely occur in these conditions.
Will water’s pH change by running over a pH tuned media? I don’t really know the science. I would assume tiny bits would dissolve?
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Looks good, @TheFire210 ! As long as you get the results you want, you can use, modify or even just ignore my off-the-cuff “advice” how ever you like! I wish you the best of luck, regardless!
Yes, @tweedledew , water in contact with ions or ionic bonds will absorb/disassociate those ions at whatever naturally favorable rate is possible (pH, pKa, etc.). Technically, yes, you might try to find perfect ratios of acid/alkali media to obtain a properly neutralized solution at elution, but doing so is nigh impossible… especially considering all the unknown variables and the fact they will change with every pass or batch!
I don’t actually know if the OP is worried about isomerization or not, but it is certainly a consideration with acidic media if the resulting resin will be heated significantly in a subsequent process.
Yes, water’s pH can change again and again as it runs over various media with different effective pH values! It happens all the time. Those media can also abstract labile cations & anions from compounds, even in non-polar solutions! That’s why any of this discussion matters, after all.
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Non ideal indeed! I will tell you that anion extraction in aprotic solvent has me thinking differently the past few years…non-ideal seems to be the way of life…quite a puzzle…
a Rubik so to speak. Moreover, it is a learning experience.
Just to point out: if one googles “salicylic acid” you will get 54 million hits.
Most of the scientific work concerns the acid base properties of the small bit of molecule built into every cannabinoic acid. All of that applies to cannabinoidic acids in “solution.”
The fact is we can on one hand think of cannabinoic acids in Butane and on the
other cannabinoic acids in Salt solutions at pH 12. It is a variegated landscape indeed.
Moreover, imagine fresh wet, fresh frozen or “dried marijauna,” say 8% H2O.
Wherever that water is , it is not water, it is component of the natural buffer of the plant.
Think about the cannabinoic acids as buffers not only in the weak acid carboxylate range
but also the pH 9.5 to 11.5 of the phenolate/rescorcinolates.
keep up the good work.
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