I agree with @cyclopath that cryogrinding is going to be the absolute best way to homogenize the gummy but I suppose if you are able to dissolved the entire gummy in water then that should work. The only problem I see with that is the more gummy you put in there the more undesirables you have to tango with. If you freeze then cut up the gummy and homogenized by hand quickly that could work for getting a smaller representative amount. I was thinking dissolving in about 20 mL water vortex for about one min sonicate for 30 minutes add 20 mL MeOH vortex for 1min sonicate 30 min then vortex for 1 min. This next part I don’t know how well it would work but if you wanted to saturate your water layer with salt that should push the MeOH and water away from each other. For 20mL I think that would take about 7.14g of NaCL. Then since you have two layers then you can just pipette off the top layer and dilute that accordingly. You’re probably going to have oils in your organic layer so maybe run through a 0.2 micron filter just in case. There is a way to check and see if your method is efficient by putting a known concentration and amount of distillate on a gummy homogenizing and then using your method to see how much you actually extracted. Also third party labs are doing it “better” because they are injecting sugars and shit onto their column and throwing them away when they don’t work anymore.
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