@DrJosh I asked explicitly if this was
- a trick you had performed?
- a trick you taught others?
- worth the effort?
- worth the price of admission.
the above response suggests it’s NOT something you’ve actually done before. I don’t have a problem with that part…so far nobody proposing recarboxylation here has.
however, your initial statement implies more intimate knowledge of the synthesis than your second.
with 30 years of synthetic chemistry behind you, it is not unreasonable that you could be fairly sure a synthetic route was available without having actually performed the synthesis.
However, when someone explicitly asks if you’ve done this before, it’s not a brilliant idea in a forum like this to ignore that question (it speaks to credibility).
You then give a vague, hand waving description, of how it might be achieved. The functional groups you refer to have names. use them. the required synthetic reactions have names. use them. the tools required have names. etc…not doing so brings the claim of 30 years playing this game into question. you see that right?
IF you were selling/teaching this technique, keeping exact details to yourself would certainly be appropriate. Which is why I asked it that was the case.
Because you didn’t respond, the reader is required to guess. My guess is that you haven’t done it. Don’t sell it. And couldn’t perform the trick today without additional reading or R&D. Others are making even less charitable guesses. based on what you have, and have not said.
currently your “me too” post ads little to the discussion…and imo diminishes your credibility. which seems counter productive for a vendor or consultant.
in no way am I suggesting you refrain from commenting. nor am I claiming that your proposed synthetic route is bunk. You didn’t come close to providing enough information for me to draw that conclusion.