A friend called me up the other day and said they have been using butane to pass their product through a pressurized LC column(silica). To my surprise he said they get a product on the other end that “sugars” quickly and basically becomes “sauce” after this process.
Anyone have, or have heard of, similar anecdotes?
butane + pressure redissolves thca
I haven’t tried this yet, but it was an idea I had I wasn’t ready to share yet. Everybody will figure everything out eventually 
how do they fraction it? by time, or how it looks?
I’m not sure what effect the silica column would have? I guess an inline for defatting, and some color reduction maybe… But what else? I am eventually going to plan a full purification pilot plant with the chromatography inline, once we have our media situation all figured out here. Have a few other things I need to finish before too, in designing my columns.
I need to take a vacation soon though, ugh I’m about dead mentally lol.
if u collect the elution in separate fractions its like chromatography with pure hexane. at least thats my understanding
I have ran hundreds of columns as a synthetic organic chemist of differnt shapes sizes and solvent systems. You can ask me any specific questions.
ever run co2 expanded solvent chromatography?
What are some of the lowest-boiling mobile phases you have worked with?
Also, given the specs on a column (BPG - GE Life Sciences) could you source me replacement seals? I have not taken it apart to see how many seals there even are.
Never ran myself. We do not use these systems in general for the type of organic chemistry I have done research on. However I do understand these systems, do you have a specific question about them?
Im working on developing a system right now that incorporates it and im having trouble finding people with experience with it. I understand the theory and have gbs of pdfs an almost every aspect but certain data i cant get good sources for. most notably the co2-ethanol mixture solubility/equilibrium data down to 200 kelvin. nothing ive seen goes below 270 k except one patent which says u can make co2-etoh mixtures of 80-20 at atmospheric pressure if at -80c
co2, butane, pentane. Do you have any issues that need to be solved? I can generally apply my chemistry knowledge to specific issues and solve them. fell free to private message as well
I already did, I just forgot to follow up to your reply. My bad. …