Ok next challenge those that have any info please share
I would like to do a Cbd isomerization in revurse so
Cbd D9 > Cbd D8 > THC D8
Want to find a good substitute for the solvent HMPA and parameters in Wich these rxn work
Confused
Cbd as we know it is Cbd delta 9
By first isomerizing the cbd to Cbd delta 8
And then to thc delta 8 we might find new methods
Get some base liable alcohol protection groups and do an acid reaction as normal? Use acid reagents that have no appreciable reaction with alkenes
Are you implying that a sort of memory exists)
Has anyone prepared d8 cbd yet? I haven’t seen it
I feel like I’ve been making it accidentally for a while now but that’s just a guess
Have you considered TPPA
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.201101830
Maybe a phase transfer catalyst? That could help enhance an sn2 reaction without hmpa and use a less scary base.
Some Cbd s are psycho active
I don’t doubt that… It’s definitely a compound I’d be interested in seeing. I take it you’ve seen it? I don’t know a method for preparing it off the top of my head.
No it s still legend Adams fed it to the rhesus monkeys and reported they behaved as in thc
Are those the monkeys with a candy shell and peanut butter filling?