Greetings.
We are a company in Sweden that are looking for consulting in removing THC from our hemp derived EtOH crude. Our government just classified CBD products with 0,2% THC narcotics… So we need to find a way to get it to 0%.
We know that people are doing it using chromatography. We dont know much about it though, but we want to learn. And we will pay for any knowledge, help & SOP.
I think about $6k/column. Can do 100-120 runs on that though. All in remediation cost is about $450-500/kg input distillate.
The Buchi systems are tiny and from my conversations with them they don’t seem to have the auto sampling capability of interchim. We can run 24 hours/day as long as we have enough solvent and large enough reservoirs added.
All of them have experience in the hemp market now and can talk with you about it to one degree or another. There is also CPC (centrifugal partitioning chromatography) which uses less solvent typically but is much more expensive for the equipment. Vendors there include:
Met with Buchi NA last week. They’ve got a few ready to ship. Really rate limited (1kg/24hr) compared to the Interchim 420 & 800 models. It would work for @enoah for your 5kg/wk. Buchi has an ELSD detector and a UV detector, where the interchim only has a UV detector and the buchi is really a higher quality unit IMHO. With the autosampler, it will run unattended. Cost was comparable to the 420, but be sure to get the autosampler and larger column options. Both use a C18 variant for column media (interchim’s is proprietary iirc). Water and Ethanol for mobile phase, acetone for column cleaning.
Plan on having a dedicated rotovap or two along for the ride. Use new ethanol for the remediation then purify and use in your extraction.