This is random, but I am curious how hard it is to make a transdermal gel? I can’t seem to find any information on here on transdermal gel. I am interested in patch like administrative methods, and would love some help on this.
Thank y’all
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you can look into the patent 3M holds on transdermal patches, that will give you a starting point on what to do as well as what you cant.
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the company that makes CBD patches for one of my clients uses the acrylic adhesive patches for reservoir transdermal delivery. Meaning it has a pocket with cbd in it. We sonicate the extract to increase bioavailability (yes, I know the controversy. Not our product, not our decisions). In honesty not really something easy to manufacture without proper equipment.
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What are you using as a transdermal carrier?
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Consider in addition to patents, researching phase 1, 2, clinical trials, and the PKs (pharmacokinetic bioassays) surrounding approved transdermals, notably approved FTIH (first time in human).
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Limonene and dmso are able to take cannabinoids across the skin barrier readily. If yiu want it to be slow release thats beyond my knowledge
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I’ve read that dmso isn’t safe since it take so everything across