Does anyone here notice a difference in amount of isomerization/azulene when distilling with the adsorbent in the flask vs filtering out the adsorbent with a silica bed… I collected about 75ml of azulene after distilling 1liter with adsorbent distilled in the RBF. Was wondering if I’d get the same amount of azulene if I filtered the adsorbent out

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Azulene is a collection of isomers which are created when the adsorband interacts with water-soluble compounds under deep vacuum during distillation (I usually see Azulene come out between 130-152°C vapor temp and <500 mtorr ).